Hirschsprung-associated enterocolitis: prevention and therapy

PK Frykman, SS Short - Seminars in pediatric surgery, 2012 - Elsevier
Hirschsprung-associated enterocolitis remains the greatest cause of morbidity and mortality
in children with Hirschsprung disease. This chapter details the various approaches used to …

Practical pathology and genetics of Hirschsprung's disease

RP Kapur - Seminars in pediatric surgery, 2009 - Elsevier
Diagnosis and management of Hirschsprung's disease (HSCR) requires understanding of
the malformation's anatomic features and multigenic nature. Rectal biopsies, intraoperative …

Development of a standardized definition for Hirschsprung's-associated enterocolitis: a Delphi analysis

AC Pastor, F Osman, DH Teitelbaum, MG Caty… - Journal of pediatric …, 2009 - Elsevier
PURPOSE: The reported incidence of Hirschsprung's-associated enterocolitis (HAEC) is
extremely variable. A standardized definition would permit comparison of different studies …

Evaluation and management of persistent problems after surgery for Hirschsprung disease in a child

R Dasgupta, JC Langer - Journal of pediatric gastroenterology …, 2008 - journals.lww.com
Hirschsprung disease occurs approximately once in every 5000 live-born infants. It is
characterized by the absence of ganglion cells in the myenteric and submucosal plexuses of …

Older age at diagnosis of Hirschsprung disease decreases risk of postoperative enterocolitis, but resection of additional ganglionated bowel does not

RN Haricharan, JM Seo, DR Kelly… - Journal of pediatric …, 2008 - Elsevier
PURPOSE: This study was conducted to determine the effect of age at diagnosis and length
of ganglionated bowel resected on postoperative Hirschsprung-associated enterocolitis …

Transitional zone pull through: surgical pathology considerations

RP Kapur, AJ Kennedy - Seminars in pediatric surgery, 2012 - Elsevier
Incomplete resection of the transitional zone (TZ) between histologically normal and
aganglionic bowel in Hirschsprung disease is a putative cause of postoperative dysmotility …

[HTML][HTML] Risk factors for enterocolitis in patients with Hirschsprung disease: a retrospective observational study

D Roorda, J Oosterlaan, E van Heurn… - Journal of Pediatric …, 2021 - Elsevier
Introduction Hirschsprung-associated enterocolitis (HAEC) accounts for substantial
morbidity and mortality in patients with Hirschsprung disease (HD). The aim of this study was …

Risk factors for Hirschsprung-associated enterocolitis following Soave: a retrospective study over a decade

C Xie, J Yan, Z Zhang, W Kai, Z Wang, Y Chen - BMC pediatrics, 2022 - Springer
Background Hirschsprung-associated enterocolitis (HAEC), one of the most significant
causes of morbidity and mortality for patients with Hirschsprung disease (HSCR), can occur …

Histopathologic delineation of the transition zone in short-segment Hirschsprung disease

RP Kapur, AJ Kennedy - Pediatric and Developmental …, 2013 - journals.sagepub.com
Failure to completely resect the transition zone (TZ) between aganglionic and
neuroanatomically normal bowel (“TZ pull-through”) is considered one reason for …

Outcome comparison among laparoscopic Duhamel, laparotomic Duhamel, and transanal endorectal pull-through: a single-center, 18-year experience

S Giuliani, P Betalli, A Narciso, F Grandi… - … & Advanced Surgical …, 2011 - liebertpub.com
Purpose: Transanal endorectal pull-through has changed the treatment of Hirschsprung's
disease (HD) in the past decade. The aim of the study was to compare outcomes, obtained …