Novel drug delivery systems for the management of dry eye

N Nagai, H Otake - Advanced drug delivery reviews, 2022 - Elsevier
Dry eye disease (DED) is a frequently observed eye complaint, which has recently attracted
considerable research interest. Conventional therapy for DED involves the use of artificial …

Choriocapillaris: fundamentals and advancements

R Lejoyeux, J Benillouche, J Ong, MH Errera… - Progress in Retinal and …, 2022 - Elsevier
The choriocapillaris is the innermost structure of the choroid that directly nourishes the
retinal pigment epithelium and photoreceptors. This article provides an overview of its …

Ocular delivery of macromolecules

YC Kim, B Chiang, X Wu, MR Prausnitz - Journal of Controlled Release, 2014 - Elsevier
Biopharmaceuticals are making increasing impact on medicine, including treatment of
indications in the eye. Macromolecular drugs are typically given by physician-administered …

Subconjunctival injectable dendrimer-dexamethasone gel for the treatment of corneal inflammation

U Soiberman, SP Kambhampati, T Wu, MK Mishra… - Biomaterials, 2017 - Elsevier
Corneal inflammation is often encountered as a key pathological event in many corneal
diseases. Current treatments involve topical corticosteroids which require frequent …

[HTML][HTML] Rapidly dissolving microneedles for the delivery of steroid-loaded nanoparticles intended for the treatment of inflammatory skin diseases

H Dawud, A Abu Ammar - Pharmaceutics, 2023 - mdpi.com
Drug delivery through the skin has immense advantages compared to other routes of
administration and offers an optimal way to treat inflammatory skin diseases, where …

Novel strategies for anterior segment ocular drug delivery

K Cholkar, SP Patel, AD Vadlapudi… - Journal of ocular …, 2013 - liebertpub.com
Research advancements in pharmaceutical sciences have led to the development of new
strategies in drug delivery to anterior segment. Designing a new delivery system that can …

In vivo measurement of trabecular meshwork stiffness in a corticosteroid-induced ocular hypertensive mouse model

G Li, C Lee, V Agrahari, K Wang… - Proceedings of the …, 2019 - National Acad Sciences
Ocular corticosteroids are commonly used clinically. Unfortunately, their administration
frequently leads to ocular hypertension, ie, elevated intraocular pressure (IOP), which, in …

[HTML][HTML] Preparation and evaluation of PCL-PEG-PCL micelles as potential nanocarriers for ocular delivery of dexamethasone

M Alami-Milani, P Zakeri-Milani… - Iranian journal of …, 2018 - ncbi.nlm.nih.gov
Objective (s): Micelles have been studied as nanoparticulate drug delivery systems for
improving the topical ocular delivery of hydrophobic drugs. The objective of this study was to …

Novel dexamethasone-loaded nanomicelles for the intermediate and posterior segment uveitis

RD Vaishya, M Gokulgandhi, S Patel, M Minocha… - Aaps Pharmscitech, 2014 - Springer
Abstract Development and characterization of dexamethasone (DEX)-encapsulated
polymeric nanomicelles have been reported. A low molecular weight di-block copolymer …

Carrageenan-stabilized chitosan alginate nanoparticles loaded with ethionamide for the treatment of tuberculosis

S Abdelghany, M Alkhawaldeh, HS AlKhatib - Journal of Drug Delivery …, 2017 - Elsevier
The objective of this work was to prepare ethionamide-loaded, cross linker free, chitosan
alginate nanoparticles stabilized with varying amounts of carrageenan using simple …