Asthma remission: what is it and how can it be achieved?

D Thomas, VM McDonald, ID Pavord… - European Respiratory …, 2022 - Eur Respiratory Soc
Asthma treatment goals currently focus on symptom and exacerbation control rather than
remission. Remission is not identical to cure, but is a step closer. This review considers the …

A review on the pathophysiology of asthma remission

OA Carpaij, JK Burgess, HAM Kerstjens… - Pharmacology & …, 2019 - Elsevier
Asthma is a chronic respiratory condition, which is highly prevalent worldwide. Although no
cure is currently available, it is well recognized that some asthma patients can …

Remission of persistent childhood asthma: Early predictors of adult outcomes

AL Wang, S Datta, ST Weiss, KG Tantisira - Journal of Allergy and Clinical …, 2019 - Elsevier
Background Few data exist on the predictors of asthma remission by early adulthood in
North America. Objective The predictors of adult asthma remission were determined in a …

Defining response to therapy with biologics in severe asthma: from global evaluation to super response and remission

AI Papaioannou, E Fouka, K Bartziokas… - Expert Review of …, 2023 - Taylor & Francis
Introduction In recent years, monoclonal antibodies targeting Type-2 inflammatory pathways
have been developed for severe asthma treatment. However, even when patients are …

[HTML][HTML] Predicting the course of asthma from childhood until early adulthood

HJL Koefoed, JM Vonk… - Current opinion in allergy …, 2022 - journals.lww.com
Lung function, allergic comorbidity and polysensitization in childhood predict the course of
asthma. Recent epigenetic studies have provided a better understanding of underlying …

Effect of the COVID-19 lockdown on asthma biological rhythms

G Hazan, C Fox, E Eiden, N Anderson… - Journal of biological …, 2022 - journals.sagepub.com
Asthma has a striking temporal character, in which time-of-day, patient age, and season
each influence disease activity. The extent to which rhythms in asthma activity reflect …

Epigenome-wide association study identifies DNA methylation markers for asthma remission in whole blood and nasal epithelium

C Qi, JM Vonk, DA van der Plaat… - Clinical and translational …, 2020 - Springer
Background Asthma is a chronic respiratory disease which is not curable, yet some patients
experience spontaneous remission. We hypothesized that epigenetic mechanisms may be …

Age-dependent reduction in asthmatic pathology through reprogramming of postviral inflammatory responses

G Hazan, A Eubanks, C Gierasch… - The Journal of …, 2022 - journals.aai.org
Asthma is a chronic disease of childhood, but for unknown reasons, disease activity
sometimes subsides as children mature. In this study, we present clinical and animal model …

Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation

T Koopmans, L Hesse, MC Nawijn, K Kumawat… - Scientific reports, 2020 - nature.com
Asthma is a heterogeneous disease characterized by chronic inflammation and structural
changes in the airways. The airway smooth muscle (ASM) is responsible for airway …

Asthma remission disparities among US youth by sexual identity and race/ethnicity, 2009-2017

CW Curry, D Felt, K Kan, M Ruprecht, X Wang… - The Journal of Allergy …, 2021 - Elsevier
Background Sexual minority and racial/ethnic minority youth experience a higher burden of
asthma. The frameworks of minority stress theory and intersectionality suggest that sexual …