Search for origins of anti-CRISPR proteins by structure comparison
Many bacterial and archaeal viruses encode anti-CRISPR proteins (Acrs) that specifically
inhibit CRISPR-Cas systems via various mechanisms. The majority of the Acrs are small …
inhibit CRISPR-Cas systems via various mechanisms. The majority of the Acrs are small …
Anti-mutagenic agent targeting LexA to combat antimicrobial resistance in mycobacteria
C Chatterjee, GR Mohan, HV Chinnasamy… - Journal of Biological …, 2024 - jbc.org
Antimicrobial resistance (AMR) is a serious global threat demanding innovations for effective
control of pathogens. The bacterial SOS response, regulated by the master regulators, LexA …
control of pathogens. The bacterial SOS response, regulated by the master regulators, LexA …
[HTML][HTML] Assessment of the Efficacy of the Antihistamine Drug Rupatadine Used Alone or in Combination against Mycobacteria
X Tian, W Ma, B Yusuf, B Su, J Hu, T Zhang - Pharmaceutics, 2024 - mdpi.com
The emergence of drug-resistant mycobacteria has rendered many clinical drugs and
regimens ineffective, imposing significant economic and healthcare burden on individuals …
regimens ineffective, imposing significant economic and healthcare burden on individuals …
Biochemical and steady-state kinetic analyses of arsenate reductases from an arsenic-tolerant strain of Citrobacter youngae IITK SM2
Arsenic (As) poisoning in aquifers is a serious problem worldwide, especially in the middle-
Gangetic Plain (MGP) of India. Microbially-mediated As speciation in such aquifers is …
Gangetic Plain (MGP) of India. Microbially-mediated As speciation in such aquifers is …
Boronic acid derivative inhibits LexA mediated SOS response in Mycobacteria
C Chatterjee, GR Mohan, VC Hariharan, B Biswas… - bioRxiv, 2023 - biorxiv.org
Antimicrobial resistance (AMR) properties of several pathogens pose as one of the major
global concerns demanding continuous innovation in order to be controlled. The bacterial …
global concerns demanding continuous innovation in order to be controlled. The bacterial …