In the modern scenario, the quinolone scaffold has emerged as a very potent motif
considering its clinical significance. Quinolones possess wide range of pharmacological …

Escherichia coli (E. coli) is the most common pathogen in both hospital and community
settings, and is capable of causing infections that can lead to serious consequences …

The chemistry of quinolones, representing one of the major classes of nitrogen-containing
heterocyclics, has received more attention and considered one of the promising …

A series of new pyridine-1, 2, 4-triazole-tagged 1, 2, 3-triazole hybrid molecules were
obtained. The new compounds were synthesized via click chemistry of 1, 2, 4-triazole-3 …

More than 300 million people suffer from the incidence of life‐threatening invasive fungal
infections, resulting in over 1.35 million deaths annually. Currently, the antifungal agents …

The quinoline scaffold has become an important construction motif for the development of
new drugs. The quinolones and their heteroannulated derivatives have high importance due …

This review examines current trends in the use of readily accessible acyclic enaminodiones
in the synthesis of heterocyclic structures, including medicinal and natural compounds …

Antibiotic-resistant bacteria are a serious global health threat, making infections harder to
treat and increasing medical costs and mortality rates. To combat resistant bacterial strains …

Cancer is one of the leading causes of death worldwide, and it has a major impact on public
health. Phosphatidylinositol 3‐kinase (PI3Kα) has been recognized as a promising drug …

The reaction of N'-(aryl) benzothiohydrazides with 2-chloro-7-cyclopropyl-3-nitro-4-
oxothieno [2, 3-b] pyridine-5-carboxylic ester/acid in the presence of triethylamine furnished …