[HTML][HTML] Protein–protein interaction prediction with deep learning: A comprehensive review

F Soleymani, E Paquet, H Viktor, W Michalowski… - Computational and …, 2022 - Elsevier
Most proteins perform their biological function by interacting with themselves or other
molecules. Thus, one may obtain biological insights into protein functions, disease …

Recent advances in predicting protein–protein interactions with the aid of artificial intelligence algorithms

S Li, S Wu, L Wang, F Li, H Jiang, F Bai - Current Opinion in Structural …, 2022 - Elsevier
Protein–protein interactions (PPIs) are essential in the regulation of biological functions and
cell events, therefore understanding PPIs have become a key issue to understanding the …

Improving protein-protein interactions prediction accuracy using XGBoost feature selection and stacked ensemble classifier

C Chen, Q Zhang, B Yu, Z Yu, PJ Lawrence… - Computers in biology …, 2020 - Elsevier
Protein-protein interactions (PPIs) are involved with most cellular activities at the proteomic
level, making the study of PPIs necessary to comprehending any biological process …

Multifaceted protein–protein interaction prediction based on Siamese residual RCNN

M Chen, CJT Ju, G Zhou, X Chen, T Zhang… - …, 2019 - academic.oup.com
Motivation Sequence-based protein–protein interaction (PPI) prediction represents a
fundamental computational biology problem. To address this problem, extensive research …

Sequence-based prediction of protein protein interaction using a deep-learning algorithm

T Sun, B Zhou, L Lai, J Pei - BMC bioinformatics, 2017 - Springer
Abstract Background Protein-protein interactions (PPIs) are critical for many biological
processes. It is therefore important to develop accurate high-throughput methods for …

LightGBM-PPI: Predicting protein-protein interactions through LightGBM with multi-information fusion

C Chen, Q Zhang, Q Ma, B Yu - Chemometrics and Intelligent Laboratory …, 2019 - Elsevier
Protein-protein interactions (PPIs) play an important role in cell life activities such as
transcriptional regulation, signal transduction and drug signal transduction. The study of …

Learning spatial structures of proteins improves protein–protein interaction prediction

B Song, X Luo, X Luo, Y Liu, Z Niu… - Briefings in …, 2022 - academic.oup.com
Spatial structures of proteins are closely related to protein functions. Integrating protein
structures improves the performance of protein–protein interaction (PPI) prediction …

Predicting protein–protein interactions through sequence-based deep learning

S Hashemifar, B Neyshabur, AA Khan, J Xu - Bioinformatics, 2018 - academic.oup.com
Motivation High-throughput experimental techniques have produced a large amount of
protein–protein interaction (PPI) data, but their coverage is still low and the PPI data is also …

DeepPPI: boosting prediction of protein–protein interactions with deep neural networks

X Du, S Sun, C Hu, Y Yao, Y Yan… - Journal of chemical …, 2017 - ACS Publications
The complex language of eukaryotic gene expression remains incompletely understood.
Despite the importance suggested by many proteins variants statistically associated with …

Improved global protein homolog detection with major gains in function identification

M Kilinc, K Jia, RL Jernigan - Proceedings of the National …, 2023 - National Acad Sciences
There are several hundred million protein sequences, but the relationships among them are
not fully available from existing homolog detection methods. There is an essential need for …