[HTML][HTML] Agent Orange reviewed: Potential role in peripheral neuropathy and neurodegeneration

SM de la Monte, A Goel - Journal of military and veterans' health, 2022 - ncbi.nlm.nih.gov
Agent Orange, a dioxin-containing toxin, was used as an herbicide during the Vietnam War.
Exposures to Agent Orange were initially linked to birth defects among Vietnamese civilians …

The neuroprotective effect of mesna on cisplatin-induced neurotoxicity: behavioral, electrophysiological, and molecular studies

H Saadati, S Noroozzadeh, H Esmaeili… - Neurotoxicity …, 2021 - Springer
Peripheral neuropathy and cognitive impairments following cisplatin administration may
interfere with the clinical usage of the drug. Mesna is a chemoprotective agent with anti …

Exposure to the herbicide 2, 4-dichlorophenoxyacetic acid impairs mitochondrial function, oxidative status, and behavior in adult zebrafish

NA Thiel, A Sachett, SE Schneider, C Garbinato… - … Science and Pollution …, 2020 - Springer
Dichlorophenoxyacetic acid (2, 4-D) is one of the most commonly used herbicides
worldwide. While the effects of 2, 4-D in target organisms are well known, its consequences …

Anti-angiogenic effects of aqueous extract from Agrostemma githago L. seed in human umbilical vein endothelial cells via regulating Notch/VEGF, MMP2/9, ANG2 …

A Niapour, M Miran, N Seyedasli, F Norouzi - Environmental Science and …, 2023 - Springer
Abnormal angiogenesis contributes to the pathogenesis of various diseases. The medicinal
usage of Agrostemma githago L. seed (A. githago herein) has been stated in traditional …

Acquisition of paclitaxel resistance modulates the biological traits of gastric cancer AGS cells and facilitates epithelial to mesenchymal transition and angiogenesis

A Niapour, N Seyedasli - Naunyn-Schmiedeberg's Archives of …, 2022 - Springer
Purpose This study aims to develop a paclitaxel (PTX)-resistant gastric cancer AGS cells
(AGS-R) and evaluate the mechanisms of drug resistance. Methods AGS cells were …

Combination treatment of all-trans retinoic acid (ATRA) and γ-secretase inhibitor (DAPT) cause growth inhibition and apoptosis induction in the human gastric cancer …

E Patrad, A Niapour, F Farassati, M Amani - Cytotechnology, 2018 - Springer
Current medication for gastric cancer patients has a low success rate with resistance and
side effects. According to recent studies, γ-secretase inhibitors is used as therapeutic drugs …

Association between 2, 4-dichlorophenoxyacetic acid and cognitive impairment in older adults: a cross-sectional study from NHANES 2001–2002 and 2011–2014

X Zou, Y Shi, J Su, Q Ye, F Lin, G Cai - Journal of Exposure Science & …, 2024 - nature.com
Abstract Background 2, 4-Dichlorophenoxyacetic acid (2, 4-D) is reported to be the most
widely used herbicide in home and garden environments, rendering it commonly …

2, 4-D causes oxidative stress induction and apoptosis in human dental pulp stem cells (hDPSCs)

S Mahmoudinia, A Niapour… - … Science and Pollution …, 2019 - Springer
Dicholorophenoxy acetic acid (2, 4-D) is a worldwide used hormone herbicide. Human
dental pulp stem cells (hDPSCs) as a potential source of mesenchymal stem cells provide a …

Agent Orange Herbicidal Toxin-Initiation of Alzheimer-Type Neurodegeneration

SM de la Monte, M Tong - Journal of Alzheimer's Disease, 2024 - content.iospress.com
Background: Agent Orange (AO) is a Vietnam War-era herbicide that contains a 1: 1 ratio of
2, 4-dichlorophenoxyacetic acid (2, 4-D) and 2, 4, 5-trichlorophenoxyacetic acid (2, 4, 5-T) …

Agent Orange causes metabolic dysfunction and molecular pathology reminiscent of Alzheimer's disease

SM de la Monte, A Goel, M Tong… - Journal of Alzheimer's …, 2023 - content.iospress.com
Background: Agent Orange, an herbicide used during the Vietnam War, contains 2, 4-
dichlorophenoxyacetic acid (2, 4-D) and 2, 4, 5-trichlorophenoxyacetic acid (2, 4, 5-T). Agent …