Boosting pathogen genomics and bioinformatics workforce in Africa

H Onywera, P Ondoa, F Nfii, A Ogwell… - The Lancet Infectious …, 2024 - thelancet.com
Next-generation sequencing (NGS) of genomic data has established its fundamental value
in public health surveillance, research and development, and precision medicine. In Africa …

[HTML][HTML] Understanding dengue virus evolution to support epidemic surveillance and counter-measure development

S Pollett, MC Melendrez, IM Berry, S Duchêne… - Infection, Genetics and …, 2018 - Elsevier
Dengue virus (DENV) causes a profound burden of morbidity and mortality, and its global
burden is rising due to the co-circulation of four divergent DENV serotypes in the ecological …

[HTML][HTML] Limited resources of genome sequencing in developing countries: challenges and solutions

M Helmy, M Awad, KA Mosa - Applied & translational genomics, 2016 - Elsevier
The differences between countries in national income, growth, human development and
many other factors are used to classify countries into developed and developing countries …

Reproducible, portable, and efficient ancient genome reconstruction with nf-core/eager

JAF Yates, TC Lamnidis, M Borry, AA Valtueña… - PeerJ, 2021 - peerj.com
The broadening utilisation of ancient DNA to address archaeological, palaeontological, and
biological questions is resulting in a rising diversity in the size of laboratories and scale of …

H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa

NJ Mulder, E Adebiyi, R Alami, A Benkahla… - Genome …, 2016 - genome.cshlp.org
The application of genomics technologies to medicine and biomedical research is
increasing in popularity, made possible by new high-throughput genotyping and sequencing …

Development of bioinformatics infrastructure for genomics research

NJ Mulder, E Adebiyi, M Adebiyi, S Adeyemi, A Ahmed… - Global heart, 2017 - Elsevier
Background Although pockets of bioinformatics excellence have developed in Africa,
generally, large-scale genomic data analysis has been limited by the availability of expertise …

Expanding research capacity in Sub-Saharan Africa through informatics, bioinformatics, and data science training programs in Mali

JG Shaffer, FJ Mather, M Wele, J Li, CO Tangara… - Frontiers in …, 2019 - frontiersin.org
Bioinformatics and data science research have boundless potential across Africa due to its
high levels of genetic diversity and disproportionate burden of infectious diseases, including …

Human OMICs and computational biology research in Africa: current challenges and prospects

Y Hamdi, L Zass, H Othman, F Radouani… - OMICS: A Journal of …, 2021 - liebertpub.com
Following the publication of the first human genome, OMICs research, including genomics,
transcriptomics, proteomics, and metagenomics, has been on the rise. OMICs studies …

Capacity building for whole genome sequencing of Mycobacterium tuberculosis and bioinformatics in high TB burden countries

E Rivière, TH Heupink, N Ismail… - Briefings in …, 2021 - academic.oup.com
Background Whole genome sequencing (WGS) is increasingly used for Mycobacterium
tuberculosis (Mtb) research. Countries with the highest tuberculosis (TB) burden face …

Bioinformatics mentorship in a resource limited setting

D Jjingo, G Mboowa, I Sserwadda… - Briefings in …, 2022 - academic.oup.com
Background The two recent simultaneous developments of high-throughput sequencing and
increased computational power have brought bioinformatics to the forefront as an important …