Rhamnus alaternus Plant: Extraction of Bioactive Fractions and Evaluation of Their Pharmacological and Phytochemical Properties

A Nekkaa, A Benaissa, F Mutelet… - Antioxidants, 2021 - mdpi.com
Rhamnus alaternus, is a wild-growing shrub, belonging to the Rhamnaceae family. Widely
distributed in the Mediterranean basin, R. alaternus is used in the usual medicine in …

Synthesis, biological activity and POM/DFT/docking analyses of annulated pyrano [2, 3-d] pyrimidine derivatives: Identification of antibacterial and antitumor …

AR Bhat, RS Dongre, FA Almalki, M Berredjem… - Bioorganic …, 2021 - Elsevier
Abstract New annulated pyrano [2, 3-d] pyrimidine derivatives were synthesized with
hydroxyl, methoxy, bromine, nitrile and nitro substituents on its skeleton. The correlated …

Design, synthesis and in vitro evaluation of antitubercular and antimicrobial activity of some novel pyranopyrimidines

NR Kamdar, DD Haveliwala, PT Mistry… - European journal of …, 2010 - Elsevier
The clinical significance of pyran and pyrimidine condensed systems and the raise in
problem of multidrug resistant bacterial pathogens has directed us to synthesize …

Ecofriendly synthesis of pyrano[2,3‐d]pyrimidine derivatives and related heterocycles with anti‐inflammatory activities

MHM AbdEl‐Azim, MA Aziz, SM Mouneir… - Archiv der …, 2020 - Wiley Online Library
A versatile, efficient, clean, and facile method was used for the synthesis of pyrano [2, 3‐d]
pyrimidine derivatives by the one‐pot three‐component condensation reaction of …

The Synthesis, Antimicrobial Activity, and Molecular Docking of New 1, 2, 4-Triazole, 1, 2, 4-Triazepine, Quinoline, and Pyrimidine Scaffolds Condensed to Naturally …

AA Abu-Hashem, SA Al-Hussain - Pharmaceuticals, 2022 - mdpi.com
This study aims to synthesize a new series of furochromone derivatives, evaluate their
antimicrobial properties, and improve the permeability of potent compounds to inhibit …

Copper-carboxamide complex immobilized on nano NaY zeolite: an efficient catalyst for xanthenes synthesis

H Younesi, S Asghari, G Firouzzadeh Pasha… - Research on Chemical …, 2023 - Springer
This paper describes the direct synthesis of carboxamide-functionalized nano NaY zeolite
(CBA-Ze) to develop a new high-functionality nanocatalyst in one pot process. This surface …

Enantioselective synthesis of spiro [indoline-3, 4′-pyrano [2, 3-c] pyrazole] derivatives via an organocatalytic asymmetric Michael/cyclization cascade reaction

J Xie, XY Xing, F Sha, ZY Wu, XY Wu - Organic & Biomolecular …, 2016 - pubs.rsc.org
An efficient enantioselective synthesis of spiro [indoline-3, 4′-pyrano [2, 3-c] pyrazole]
derivatives by a cascade reaction between pyrazolones and isatylidene malononitriles is …

Biocatalytic tandem multicomponent reactions for one-pot synthesis of 2-Amino-4H-Pyran library and in vitro biological evaluation

ZJ Yang, QT Gong, Y Wang, Y Yu, YH Liu, N Wang… - Molecular …, 2020 - Elsevier
A simple, effective and ecofriendly biocatalytic method has been developed to construct 2-
amino-4H-pyrans via tandem multi-component reaction (MCR) of aldehyde, malononitrile …

Six-membered ring systems: diazines and benzo derivatives

A Manlove, MP Groziak - Progress in heterocyclic chemistry, 2009 - Elsevier
Publisher Summary This chapter reviews the syntheses and reactions of 6-membered
heterocyclic ring systems, such as diazines and benzo derivatives. The diazines pyridazine …

Design, synthesis, computational and biological evaluation of some new hydrazino derivatives of DHA and pyranopyrazoles

A Kumar, P Lohan, DK Aneja, GK Gupta… - European journal of …, 2012 - Elsevier
Two series of compounds namely, 4-aryl/heteroaryl hydrazino-3-acetyl-6-methyl-2H-pyran-2-
ones (4a–4j) and pyrano [4, 3-c] pyrazoles (6a–6e and 6g) were synthesized starting from 3 …