Autophagy is an evolutionarily conserved mechanism for intracellular substance
degradation, responsible for the recycling of metabolic substances and the maintenance of …

The extracellular matrix (ECM) exists as a dynamic network of biophysical and biochemical
factors that maintain tissue homeostasis. Given its sensitivity to changes in the intra-and …

This review presents current knowledge related to VDAC1 as a multi-functional
mitochondrial protein acting on both sides of the coin, regulating cell life and death, and …

This study aimed to investigate the protective effect of black raspberry anthocyanins (BRAs)
against acute and subacute alcoholic liver disease (ALD). Network analysis and docking …

Proteoglycans and selected extracellular matrix constituents are emerging as intrinsic and
critical regulators of evolutionarily conversed, intracellular catabolic pathways. Often, these …

Apoptotic resistance leads to persistent accumulation of senescent cells and sustained
expression of a senescence-associated secretory phenotype, playing an essential role in …

Extensive or persistent calcium phosphate deposition within soft tissues after severe
traumatic injury or major orthopedic surgery can result in pain and loss of joint function. The …

Abstract Background AD-2 (20 (R)-dammarane-3b, 12b, 20, 25-tetrol; 25-OH-PPD) is a
ginsenoside and isolated from Panax ginseng, showing anticancer activity against extensive …

Angiogenesis is a finely co-ordinated, multi-step developmental process of the new vascular
structure. Even though angiogenesis is regularly occurring in physiological events such as …

Human plasminogen kringle 5 (K5) is known to display its potent anti-angiogenesis effect
through inducing endothelial cell (EC) apoptosis, and the voltage-dependent anion channel …