Long noncoding RNAs: molecular modalities to organismal functions
We have known for decades that long noncoding RNAs (lncRNAs) can play essential
functions across most forms of life. The maintenance of chromosome length requires an …
functions across most forms of life. The maintenance of chromosome length requires an …
HOX cluster-embedded antisense long non-coding RNAs in lung cancer
L Li, Y Wang, G Song, X Zhang, S Gao, H Liu - Cancer letters, 2019 - Elsevier
Homeobox (HOX) genes play vital roles in embryonic development and oncogenesis. In
humans, there are 39 HOX genes found in four clusters that are located on different …
humans, there are 39 HOX genes found in four clusters that are located on different …
Transcriptional read-through of the long non-coding RNA SVALKA governs plant cold acclimation
Most DNA in the genomes of higher organisms does not encode proteins, yet much is
transcribed by RNA polymerase II (RNAPII) into long non-coding RNAs (lncRNAs). The …
transcribed by RNA polymerase II (RNAPII) into long non-coding RNAs (lncRNAs). The …
Lnc HAGLR promotes colon cancer progression through sponging miR‐185‐5p and activating CDK4 and CDK6 in vitro and in vivo
W Sun, W Nie, Z Wang, H Zhang, Y Li… - OncoTargets and …, 2020 - Taylor & Francis
Background/Aim LncRNA plays a key role in tumor progression. HAGLR functions as an
oncogene in many cancers. However, the molecular mechanism of HAGLR in colon cancer …
oncogene in many cancers. However, the molecular mechanism of HAGLR in colon cancer …
[HTML][HTML] Zinc finger protein 277 is an intestinal transit-amplifying cell marker and colon cancer oncogene
G Xie, Z Peng, J Liang, SM Larabee, CB Drachenberg… - JCI insight, 2022 - ncbi.nlm.nih.gov
Sustained proliferative signaling and resisting cell death are hallmarks of cancer. Zinc finger
protein 277 (ZNF277; murine Zfp277), a transcription factor regulating cellular senescence …
protein 277 (ZNF277; murine Zfp277), a transcription factor regulating cellular senescence …
Functional roles of long non-coding RNAs in motor neuron development and disease
Long non-coding RNAs (lncRNAs) have gained increasing attention as they exhibit highly
tissue-and cell-type specific expression patterns. LncRNAs are highly expressed in the …
tissue-and cell-type specific expression patterns. LncRNAs are highly expressed in the …
Long non-coding RNA HOXD-AS1 in cancer
L Li, Y Wang, X Zhang, Q Huang, Y Diao, H Yin… - Clinica chimica acta, 2018 - Elsevier
Cancer is one of the leading causes of death worldwide with a high risk of incidence and
mortality. Long non-coding RNAs (lncRNAs) have been shown to participate in various …
mortality. Long non-coding RNAs (lncRNAs) have been shown to participate in various …
A chemoresistance lncRNA signature for recurrence risk stratification of colon cancer patients with chemotherapy
Chemotherapy is considered the nonsurgical treatment of choice for colon cancer patients.
However, no precise molecular markers are available to determine which patients can …
However, no precise molecular markers are available to determine which patients can …
Comparative transcriptomics analyses across species, organs, and developmental stages reveal functionally constrained lncRNAs
F Darbellay, A Necsulea - Molecular biology and evolution, 2020 - academic.oup.com
The functionality of long noncoding RNAs (lncRNAs) is disputed. In general, lncRNAs are
under weak selective pressures, suggesting that the majority of lncRNAs may be …
under weak selective pressures, suggesting that the majority of lncRNAs may be …
Hox proteins in the regulation of muscle development
G Poliacikova, C Maurel-Zaffran, Y Graba… - Frontiers in Cell and …, 2021 - frontiersin.org
Hox genes encode evolutionary conserved transcription factors that specify the anterior–
posterior axis in all bilaterians. Being well known for their role in patterning ectoderm …
posterior axis in all bilaterians. Being well known for their role in patterning ectoderm …