Mechanisms underlying gain modulation in the cortex

KA Ferguson, JA Cardin - Nature Reviews Neuroscience, 2020 - nature.com
Cortical gain regulation allows neurons to respond adaptively to changing inputs. Neural
gain is modulated by internal and external influences, including attentional and arousal …

Spatial attention alters visual appearance

M Carrasco, A Barbot - Current opinion in psychology, 2019 - Elsevier
Highlights•Covert attention improves sensory processing in many visual tasks.•Covert
attention also alters the appearance of visual information.•Many spatial and temporal …

Representational drift in the mouse visual cortex

D Deitch, A Rubin, Y Ziv - Current biology, 2021 - cell.com
Recent studies have shown that neuronal representations gradually change over time
despite no changes in the stimulus, environment, or behavior. However, such …

Miniscope-LFOV: a large-field-of-view, single-cell-resolution, miniature microscope for wired and wire-free imaging of neural dynamics in freely behaving animals

C Guo, GJ Blair, M Sehgal, FN Sangiuliano Jimka… - Science …, 2023 - science.org
Imaging large-population, single-cell fluorescent dynamics in freely behaving animals larger
than mice remains a key endeavor of neuroscience. We present a large-field-of-view open …

Locomotion enhances neural encoding of visual stimuli in mouse V1

MC Dadarlat, MP Stryker - Journal of Neuroscience, 2017 - Soc Neuroscience
Neurons in mouse primary visual cortex (V1) are selective for particular properties of visual
stimuli. Locomotion causes a change in cortical state that leaves their selectivity unchanged …

Activity in primate visual cortex is minimally driven by spontaneous movements

BC Talluri, I Kang, A Lazere, KR Quinn, N Kaliss… - Nature …, 2023 - nature.com
Organisms process sensory information in the context of their own moving bodies, an idea
referred to as embodiment. This idea is important for developmental neuroscience, robotics …

NMDA-driven dendritic modulation enables multitask representation learning in hierarchical sensory processing pathways

WAM Wybo, MC Tsai, VAK Tran… - Proceedings of the …, 2023 - National Acad Sciences
While sensory representations in the brain depend on context, it remains unclear how such
modulations are implemented at the biophysical level, and how processing layers further in …

EZcalcium: open-source toolbox for analysis of calcium imaging data

DA Cantu, B Wang, MW Gongwer, CX He… - Frontiers in neural …, 2020 - frontiersin.org
Fluorescence calcium imaging using a range of microscopy approaches, such as two-
photon excitation or head-mounted “miniscopes,” is one of the preferred methods to record …

Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible

A Goel, DA Cantu, J Guilfoyle, GR Chaudhari… - Nature …, 2018 - nature.com
To uncover the circuit-level alterations that underlie atypical sensory processing associated
with autism, we adopted a symptom-to-circuit approach in the Fmr1-knockout (Fmr1–/–) …

The mouse superior colliculus: an emerging model for studying circuit formation and function

S Ito, DA Feldheim - Frontiers in neural circuits, 2018 - frontiersin.org
The superior colliculus (SC) is a midbrain area where visual, auditory and somatosensory
information are integrated to initiate motor commands. The SC plays a central role in visual …