De novo lipogenesis (DNL) is a complex and highly regulated process in which
carbohydrates from circulation are converted into fatty acids that are then used for …

The present article comprehensively reviews the macromolecular synthesis using enzymes
as catalysts. Among the six main classes of enzymes, the three classes, oxidoreductases …

Sialic acids are cytoprotectors, mainly localized on the surface of cell membranes with
multiple and outstanding cell biological functions. The history of their structural analysis …

Recombinant protein production emerged in the early 1980s with the development of
genetic engineering tools, which represented a compelling alternative to protein extraction …

Much has been made about JLW Thudichum's colorful, and one could say clairvoyant,
naming of sphingosine “in commemoration of the many enigmas which it presented to the …

Lipids are produced, transported, and recognized by the concerted actions of numerous
enzymes, binding proteins, and receptors. A comprehensive analysis of lipid molecules," …

Vertebrate glycoproteins and glycolipids are synthesized in complex biosynthetic pathways
localized predominantly within membrane compartments of the secretory pathway. The …

Aberrant glycosylation occurs in essen-tially all types of experimental and human cancers,
as has been observed for over 35 years, and many glycosyl epitopes constitute tumor …

Objective Glycans attached to the Fc portion of IgG are important modulators of IgG effector
functions. Interindividual differences in IgG glycome composition are large and they …

Glycosyltransferases (GTs) catalyze the transfer of a sugar moiety from an activated donor
sugar onto saccharide and nonsaccharide acceptors. A sequence-based classification …