Sleep is highly conserved across evolution, suggesting vital biological functions that are yet
to be fully understood. Animals and humans experiencing partial sleep restriction usually …

The brain-derived neurotrophic factor (BDNF) mediates the plasticity-related changes that
associate with memory processing during sleep. Sleep deprivation and chronic stress are …

Microglia-induced neuroinflammation plays a vital role in the etiology and progression of
neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and …

Sleep is an essential physiological function that sustains human life. Sleep disorders involve
problems with the quality, duration, and abnormal behaviour of sleep. Insomnia is the most …

Males and females can respond differentially to the same environmental stimuli and
experimental conditions. Chronic sleep loss is a frequent and growing problem in many …

As the population of older adults grows, so will the prevalence of aging-related conditions,
including memory impairments and sleep disturbances, both of which are more common …

Although Parkinson's disease (PD) is well known with its motor deficits, the patients often
suffer from cognitive dysfunction. Apelin, as the endogenous ligand of the APJ receptor, is …

The modified multi-platform method (MMPM) is used to induce animal models of paradoxical
sleep deprivation and impairs memory in rodents. However, variations in MMPM protocols …

Previous studies have indicated that forced exercise plays a preventive role in synaptic
plasticity deficits in the hippocampus and behavioral impairments in sleep-deprived male …

Cognitive deficits have an extensive influence on the quality of life of the Parkinson's
disease (PD) patients. Previous studies have shown that lack of steroid hormones have an …