Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI

M Kraiger, T Klein-Rodewald, B Rathkolb… - Scientific Reports, 2022 - nature.com
Animal models are an indispensable platform used in various research disciplines,
enabling, for example, studies of basic biological mechanisms, pathological processes and …

Transgenic mouse models of SV40-induced cancer

AL Hudson, EK Colvin - ILAR journal, 2016 - academic.oup.com
The SV40 viral oncogene has been used since the 1970s as a reliable and reproducible
method to generate transgenic mouse models. This seminal discovery has taught us an …

Evaluation of nonalcoholic fatty liver disease in C57BL/6J mice by using MRI and histopathologic analyses

JE Ryu, W Jo, HJ Choi, S Jang, HJ Lee… - Comparative …, 2015 - ingentaconnect.com
Nonalcoholic fatty liver disease (NAFLD) can lead to cirrhosis, hepatocellular carcinoma,
and ultimately death. Magnetic resonance techniques are accurate, noninvasive methods for …

MRI reveals increased tumorigenesis following high fat feeding in a mouse model of triple‐negative breast cancer

D Mustafi, S Fernandez, E Markiewicz… - NMR in …, 2017 - Wiley Online Library
High animal fat consumption is associated with an increase in triple‐negative breast cancer
(TNBC) risk. Based on previous MRI studies demonstrating the feasibility of detecting very …

MRI accurately identifies early murine mammary cancers and reliably differentiates between in situ and invasive cancer: correlation of MRI with histology

D Mustafi, M Zamora, X Fan, E Markiewicz… - NMR in …, 2015 - Wiley Online Library
MRI methods that accurately identify various stages of mouse mammary cancer could
provide new knowledge that may have a direct impact on the management of breast cancer …

Functional imaging of the angiogenic switch in a transgenic mouse model of human breast cancer by dynamic contrast enhanced magnetic resonance imaging

L Consolino, DL Longo, W Dastrù… - … Journal of Cancer, 2016 - Wiley Online Library
Tumour progression depends on several sequential events that include the
microenvironment remodelling processes and the switch to the angiogenic phenotype …

Magnetic resonance angiography reveals increased arterial blood supply and tumorigenesis following high fat feeding in a mouse model of triple‐negative breast …

D Mustafi, R Valek, M Fitch, V Werner, X Fan… - NMR in …, 2020 - Wiley Online Library
Breast cancer is the second most commonly diagnosed malignancy among women globally.
Past MRI studies have linked a high animal fat diet (HAFD) to increased mammary cancer …

Magnetic resonance angiography shows increased arterial blood supply associated with murine mammary cancer

D Mustafi, A Leinroth, X Fan… - International Journal …, 2019 - Wiley Online Library
Breast cancer is a major cause of morbidity and mortality in Western women. Tumor
neoangiogenesis, the formation of new blood vessels from pre‐existing ones, may be used …

MRI ductography of contrast agent distribution and leakage in normal mouse mammary ducts and ducts with in situ cancer

E Markiewicz, X Fan, D Mustafi, M Zamora… - Magnetic resonance …, 2017 - Elsevier
High resolution 3D MRI was used to study contrast agent distribution and leakage in normal
mouse mammary glands and glands containing in situ cancer after intra-ductal injection …

CCL2/CCR2 chemokine signaling modulates ductal breast cancer progression by enhancing glycolysis and c-MET activation

DS Acevedo - 2021 - search.proquest.com
Despite therapeutic advancement, ductal carcinoma in situ (DCIS) remains the most
common form of pre-invasive breast cancer diagnosed among women with 60,000 cases …