[HTML][HTML] New pharmacological strategies to fight enveloped viruses

K Wisskirchen, J Lucifora, T Michler… - Trends in pharmacological …, 2014 - cell.com
Enveloped viruses pose an important health threat because most of the persistent and many
emerging viruses are enveloped. In particular, newly emerging viruses create a need to …

[HTML][HTML] Segmented, Negative-Sense RNA Viruses of Humans: Genetic Systems and Experimental Uses of Reporter Strains

CE Hamele, MA Spurrier, RA Leonard… - Annual Review of …, 2023 - annualreviews.org
Negative-stranded RNA viruses are a large group of viruses that encode their genomes in
RNA across multiple segments in an orientation antisense to messenger RNA. Their …

[HTML][HTML] Epigenetic targeting of the ACE2 and NRP1 viral receptors limits SARS-CoV-2 infectivity

ML Saiz, ML De Diego, D López-García… - Clinical …, 2021 - Springer
Background SARS-CoV-2 uses the angiotensin-converting enzyme 2 (ACE2) and neuropilin-
1 (NRP1) receptors for entry into cells, and the serine protease TMPRSS2 for S protein …

The ReFRAME library as a comprehensive drug repurposing library to identify mammarenavirus inhibitors

YJ Kim, B Cubitt, E Chen, MV Hull, AK Chatterjee… - Antiviral research, 2019 - Elsevier
Several mammarenaviruses, chiefly Lassa virus (LASV) in Western Africa and Junín virus
(JUNV) in the Argentine Pampas, cause severe disease in humans and pose important …

[HTML][HTML] The valproic acid derivative valpromide inhibits pseudorabies virus infection in swine epithelial and mouse neuroblastoma cell lines

S Andreu, I Ripa, B Praena, JA López-Guerrero… - Viruses, 2021 - mdpi.com
Pseudorabies virus (PRV) infection of swine can produce Aujeszky's disease, which causes
neurological, respiratory, and reproductive symptoms, leading to significant economic losses …

Identification and mechanism of action of a novel small-molecule inhibitor of arenavirus multiplication

N Ngo, B Cubitt, M Iwasaki, JC de la Torre - Journal of virology, 2015 - Am Soc Microbiol
Several arenaviruses cause hemorrhagic fever disease in humans and represent important
public health problems in the regions where these viruses are endemic. In addition …

Sodium hydrogen exchangers contribute to arenavirus cell entry

M Iwasaki, N Ngo, JC de la Torre - Journal of virology, 2014 - Am Soc Microbiol
Several arenaviruses, chiefly Lassa virus (LASV), cause hemorrhagic fever (HF) disease in
humans and pose a great public health concern in the regions in which they are endemic …

[HTML][HTML] Visualizing lymphocytic choriomeningitis virus infection in cells and living mice

Y Wen, H Xu, W Wan, W Shang, R Jin, F Zhou, H Mei… - Iscience, 2022 - cell.com
Mammarenavirus are a large family of enveloped negative-strand RNA viruses that include
several agents responsible for severe hemorrhagic fevers. Until now, no FDA-licensed drug …

Arenavirus quasispecies and their biological implications

A Grande-Pérez, V Martin, H Moreno… - … : From Theory to …, 2016 - Springer
The family Arenaviridae currently comprises over 20 viral species, each of them associated
with a main rodent species as the natural reservoir and in one case possibly phyllostomid …

[HTML][HTML] Valproic acid and its amidic derivatives as new antivirals against alphaherpesviruses

S Andreu, I Ripa, R Bello-Morales, JA López-Guerrero - Viruses, 2020 - mdpi.com
Herpes simplex viruses (HSVs) are neurotropic viruses with broad host range whose
infections cause considerable health problems in both animals and humans. In fact, 67% of …