The role of the microbiota in periodontal disease

MA Curtis, PI Diaz, TE Van Dyke - Periodontology 2000, 2020 - Wiley Online Library
The last decade has witnessed unparalleled advances in our understanding of the
complexity of the oral microbiome and the compositional changes that occur in subgingival …

The nexus between periodontal inflammation and dysbiosis

TE Van Dyke, PM Bartold, EC Reynolds - Frontiers in immunology, 2020 - frontiersin.org
The nexus between periodontal inflammation and the polymicrobial biofilm in the gingival
sulcus is critical to understanding the pathobiology of periodontitis. Both play a major role in …

Alterations of the human gut microbiome in liver cirrhosis

N Qin, F Yang, A Li, E Prifti, Y Chen, L Shao, J Guo… - Nature, 2014 - nature.com
Liver cirrhosis occurs as a consequence of many chronic liver diseases that are prevalent
worldwide. Here we characterize the gut microbiome in liver cirrhosis by comparing 98 …

The Harvest suite for rapid core-genome alignment and visualization of thousands of intraspecific microbial genomes

TJ Treangen, BD Ondov, S Koren, AM Phillippy - Genome biology, 2014 - Springer
Whole-genome sequences are now available for many microbial species and clades,
however existing whole-genome alignment methods are limited in their ability to perform …

Insights from 20 years of bacterial genome sequencing

M Land, L Hauser, SR Jun, I Nookaew… - Functional & integrative …, 2015 - Springer
Since the first two complete bacterial genome sequences were published in 1995, the
science of bacteria has dramatically changed. Using third-generation DNA sequencing, it is …

Genome sequence-based species delimitation with confidence intervals and improved distance functions

JP Meier-Kolthoff, AF Auch, HP Klenk, M Göker - BMC bioinformatics, 2013 - Springer
Background For the last 25 years species delimitation in prokaryotes (Archaea and Bacteria)
was to a large extent based on DNA-DNA hybridization (DDH), a tedious lab procedure …

MycoCosm portal: gearing up for 1000 fungal genomes

IV Grigoriev, R Nikitin, S Haridas, A Kuo… - Nucleic acids …, 2014 - academic.oup.com
MycoCosm is a fungal genomics portal (http://jgi. doe. gov/fungi), developed by the US
Department of Energy Joint Genome Institute to support integration, analysis and …

GET_HOMOLOGUES, a versatile software package for scalable and robust microbial pangenome analysis

B Contreras-Moreira, P Vinuesa - Applied and environmental …, 2013 - Am Soc Microbiol
ABSTRACT GET_HOMOLOGUES is an open-source software package that builds on
popular orthology-calling approaches making highly customizable and detailed pangenome …

Social networks predict gut microbiome composition in wild baboons

J Tung, LB Barreiro, MB Burns, JC Grenier, J Lynch… - elife, 2015 - elifesciences.org
Social relationships have profound effects on health in humans and other primates, but the
mechanisms that explain this relationship are not well understood. Using shotgun …

Intergenomic Comparisons Highlight Modularity of the Denitrification Pathway and Underpin the Importance of Community Structure for N2O Emissions

DRH Graf, CM Jones, S Hallin - PloS one, 2014 - journals.plos.org
Nitrous oxide (N2O) is a potent greenhouse gas and the predominant ozone depleting
substance. The only enzyme known to reduce N2O is the nitrous oxide reductase, encoded …