The biological and clinical significance of emerging SARS-CoV-2 variants
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
SARS-CoV-2 variants, vaccines, and host immunity
P Mistry, F Barmania, J Mellet, K Peta… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new beta coronavirus
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …
Humoral response to the Pfizer BNT162b2 vaccine in patients undergoing maintenance hemodialysis
Results All subjects in the control group developed an antibody response compared with
96%(54 of 56) positive responders in the dialysis group. The IgG levels in the dialysis group …
96%(54 of 56) positive responders in the dialysis group. The IgG levels in the dialysis group …
[HTML][HTML] SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2
F Amanat, M Thapa, T Lei, SMS Ahmed, DC Adelsberg… - Cell, 2021 - cell.com
In this study we profiled vaccine-induced polyclonal antibodies as well as plasmablast-
derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal …
derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal …
mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions
P Kaplonek, D Cizmeci, S Fischinger… - Science translational …, 2022 - science.org
The successful development of several coronavirus disease 2019 (COVID-19) vaccines has
substantially reduced morbidity and mortality in regions of the world where the vaccines …
substantially reduced morbidity and mortality in regions of the world where the vaccines …
Understanding neutralising antibodies against SARS-CoV-2 and their implications in clinical practice
NYL Pang, ASR Pang, VT Chow, DY Wang - Military Medical Research, 2021 - Springer
SARS-CoV-2 is a newly identified member of the coronavirus family that has caused the
Coronavirus disease 2019 (COVID-19) pandemic. This rapidly evolving and unrelenting …
Coronavirus disease 2019 (COVID-19) pandemic. This rapidly evolving and unrelenting …
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
The extent to which immune responses to natural infection with severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and immunization with vaccines protect against …
syndrome coronavirus 2 (SARS-CoV-2) and immunization with vaccines protect against …
mRNA-1273 vaccine-induced antibodies maintain Fc effector functions across SARS-CoV-2 variants of concern
SARS-CoV-2 mRNA vaccines confer robust protection against COVID-19, but the
emergence of variants has generated concerns regarding the protective efficacy of the …
emergence of variants has generated concerns regarding the protective efficacy of the …
[HTML][HTML] An intranasal vaccine durably protects against SARS-CoV-2 variants in mice
SARS-CoV-2 variants that attenuate antibody neutralization could jeopardize vaccine
efficacy. We recently reported the protective activity of an intranasally administered spike …
efficacy. We recently reported the protective activity of an intranasally administered spike …
Predictors and dynamics of the humoral and cellular immune response to SARS-CoV-2 mRNA vaccines in hemodialysis patients: a multicenter observational study
J Van Praet, M Reynders, D De Bacquer… - Journal of the …, 2021 - journals.lww.com
Background Preliminary evidence suggests patients on hemodialysis have a blunted early
serological response to SARS-CoV-2 vaccination. Optimizing the vaccination strategy in this …
serological response to SARS-CoV-2 vaccination. Optimizing the vaccination strategy in this …