Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Tumor microenvironment complexity and therapeutic implications at a glance

R Baghban, L Roshangar… - Cell Communication and …, 2020 - Springer
The dynamic interactions of cancer cells with their microenvironment consisting of stromal
cells (cellular part) and extracellular matrix (ECM) components (non-cellular) is essential to …

DNA functional materials assembled from branched DNA: design, synthesis, and applications

Y Dong, C Yao, Y Zhu, L Yang, D Luo… - Chemical Reviews, 2020 - ACS Publications
DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

A DNA-based hydrogel for exosome separation and biomedical applications

J Tang, X Jia, Q Li, Z Cui, A Liang… - Proceedings of the …, 2023 - National Acad Sciences
Exosomes (EXOs) have been proven as biomarkers for disease diagnosis and agents for
therapeutics. Great challenge remains in the separation of EXOs with high-purity and low …

Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021 - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture

YH Peng, SK Hsiao, K Gupta, A Ruland… - Nature …, 2023 - nature.com
Three-dimensional cell and organoid cultures rely on the mechanical support of viscoelastic
matrices. However, commonly used matrix materials lack control over key cell-instructive …

Detection and beyond: Challenges and advances in aptamer-based biosensors

H Yoo, H Jo, SS Oh - Materials Advances, 2020 - pubs.rsc.org
Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …

DNA hydrogels and microgels for biosensing and biomedical applications

F Li, D Lyu, S Liu, W Guo - Advanced Materials, 2020 - Wiley Online Library
DNA hydrogels, which take advantage of the unique properties of functional DNA motifs,
such as specific molecular recognition, programmable and high‐precision assembly …

Microneedle array encapsulated with programmed DNA hydrogels for rapidly sampling and sensitively sensing of specific microRNA in dermal interstitial fluid

Q Yang, Y Wang, T Liu, C Wu, J Li, J Cheng, W Wei… - ACS …, 2022 - ACS Publications
Author: Please verify that the changes made to improve the English still retain your original
meaning. Detection of microRNA (miRNA) in dermal interstitial fluid (ISF) has emerged as …

Thermal‐responsive MXene‐DNA hydrogel for near‐infrared light triggered localized photothermal‐chemo synergistic cancer therapy

PP He, X Du, Y Cheng, Q Gao, C Liu, X Wang, Y Wei… - Small, 2022 - Wiley Online Library
Stimuli‐responsive DNA hydrogels are promising candidates for cancer treatment, as they
not only possess biocompatible and biodegradable 3D network structures as highly efficient …