This review follows the research, development and clinical applications of the
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …

Photochemical internalisation (PCI) is a unique intervention which involves the release of
endocytosed macromolecules into the cytoplasmic matrix. PCI is based on the use of …

Oral cancer is the sixth most common malignant cancer, affecting the health of people with
an unacceptably high mortality rate. Despite numerous clinical methods in the diagnosis and …

This review briefly summaries the principles and mechanisms of action of photodynamic
therapy (PDT) as concerns its application in the oncological field, highlighting its drawbacks …

Efficient photodynamic therapy with meta-tetra (hydroxyphenyl) chlorine requires the
application of specific nanoformulations. mTHPC liposomal formulation (Foslip®) …

Despite specialists' efforts to find the best solutions for cancer diagnosis and therapy, this
pathology remains the biggest health threat in the world. Global statistics concerning deaths …

In cancer photodynamic therapy (PDT), an efficient and homogeneous intratumoral
accumulation of the photosensitizer (PS) is required to induce cell damages in the entire …

Today, a growing number of nanotherapeutics is utilized to deliver poorly soluble
compounds using the intravenous route of administration. The drug release and the direct …

The potential of photoactivating certain molecules, photosensitizers (PS), resulting in
photochemical processes, has long been realized in the form of photodynamic therapy …

The combined use of a photosensitizing agent, light and dioxygen for the treatment of
diseases has become known as photodynamic therapy (PDT) and was first discovered more …