Microtubules are dynamic polymers of αβ-tubulin that are essential for intracellular
organization, organelle trafficking and chromosome segregation. Microtubule growth and …

Microtubules are cytoskeletal filaments central to a wide range of essential cellular functions
in eukaryotic cells. Consequently, cells need to exert tight control over when, where and how …

Dissipative self-assembly is ubiquitous in nature, where it gives rise to complex structures
and functions such as self-healing, homeostasis, and camouflage. These phenomena are …

One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

Mitotic catastrophe, as defined in 2012 by the International Nomenclature Committee on Cell
Death, is a bona fide intrinsic oncosuppressive mechanism that senses mitotic failure and …

The dynamic instability of microtubules is characterized by slow growth phases
stochastically interrupted by rapid depolymerizations called catastrophes. Rescue events …

Living systems are capable of locomotion, reconfiguration and replication. To perform these
tasks, cells spatiotemporally coordinate the interactions of force-generating,'active'molecules …

The inter-neuronal communication occurring in extensively branched neuronal cells is
achieved primarily through the microtubule (MT)-mediated axonal transport system. This …

Mitotic catastrophe is distinct from other cell death modes due to unique nuclear alterations
characterized as multi and/or micronucleation. Mitotic catastrophe is a common and virtually …

Aging is a complex feature and involves loss of multiple functions and nonreversible
phenotypes. However, several studies suggest it is possible to protect against aging and …