A positive feedback loop of Hippo-and c-Jun-amino-terminal kinase signaling pathways regulates amyloid-beta-mediated neurodegeneration
Alzheimer's disease (AD, OMIM: 104300) is an age-related disorder that affects millions of
people. One of the underlying causes of AD is generation of hydrophobic amyloid-beta 42 …
people. One of the underlying causes of AD is generation of hydrophobic amyloid-beta 42 …
A soy protein Lunasin can ameliorate amyloid-beta 42 mediated neurodegeneration in Drosophila eye
Abstract Alzheimer's disease (AD), a fatal progressive neurodegenerative disorder, also
results from accumulation of amyloid-beta 42 (Aβ42) plaques. These Aβ42 plaques trigger …
results from accumulation of amyloid-beta 42 (Aβ42) plaques. These Aβ42 plaques trigger …
[HTML][HTML] Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo
Abstract Amyotrophic Lateral Sclerosis (ALS), a late-onset neurodegenerative disorder
characterized by the loss of motor neurons in the central nervous system, has no known cure …
characterized by the loss of motor neurons in the central nervous system, has no known cure …
Unbiased automated quantitation of ROS signals in live retinal neurons of Drosophila using Fiji/ImageJ
Numerous imaging modules are utilized to study changes that occur during cellular
processes. Besides qualitative (immunohistochemical) or semiquantitative (Western blot) …
processes. Besides qualitative (immunohistochemical) or semiquantitative (Western blot) …
Generation of Third Dimension: Axial Patterning in the Developing Drosophila Eye
Axial patterning, a fundamental process during organogenesis, is required for transition of a
single layer organ primordium to a three-dimensional organ in all multi-cellular organisms …
single layer organ primordium to a three-dimensional organ in all multi-cellular organisms …
Proximal fate marker homothorax marks the lateral extension of stalk‐eyed fly Cyrtodopsis whitei
The placement of eyes on insect head is an important evolutionary trait. The stalk‐eyed fly,
Cyrtodopsis whitei, exhibits a hypercephaly phenotype where compound eyes are located …
Cyrtodopsis whitei, exhibits a hypercephaly phenotype where compound eyes are located …
Motif 1 Binding Protein suppresses wingless to promote eye fate in Drosophila
The phenomenon of RNA polymerase II (Pol II) pausing at transcription start site (TSS) is
one of the key rate-limiting steps in regulating genome-wide gene expression. In Drosophila …
one of the key rate-limiting steps in regulating genome-wide gene expression. In Drosophila …
SARS-CoV2 Nsp3 protein triggers cell death and exacerbates amyloid β42-mediated neurodegeneration
A Singh, AV Chimata, P Deshpande… - Neural Regeneration …, 2024 - journals.lww.com
Infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2)
virus, responsible for the coronavirus disease 2019 (COVID-19) pandemic, induces …
virus, responsible for the coronavirus disease 2019 (COVID-19) pandemic, induces …
Early eye development: Specification and determination
AK Mishra, SG Sprecher - Molecular genetics of axial patterning, growth …, 2020 - Springer
Making of an eye requires commitment of cells to adopt an eye tissue fate by the process of
retinal specification and determination. Basic molecular mechanisms to form an eye depend …
retinal specification and determination. Basic molecular mechanisms to form an eye depend …
An E3 ubiquitin ligase, cullin‐4 regulates retinal differentiation in Drosophila eye
During organogenesis, cell proliferation is followed by the differentiation of specific cell types
to form an organ. Any aberration in differentiation can result in developmental defects, which …
to form an organ. Any aberration in differentiation can result in developmental defects, which …