[HTML][HTML] Determinants of resident tissue macrophage identity and function

C Blériot, S Chakarov, F Ginhoux - Immunity, 2020 - cell.com
Resident tissue macrophages (RTMs) have a broad spectrum of immune-and non-immune-
related tissue-supporting activities. The roots of this heterogeneity and versatility are only …

Isothermal amplification of nucleic acids

Y Zhao, F Chen, Q Li, L Wang, C Fan - Chemical reviews, 2015 - ACS Publications
Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …

[HTML][HTML] The gut virome database reveals age-dependent patterns of virome diversity in the human gut

AC Gregory, O Zablocki, AA Zayed, A Howell… - Cell host & …, 2020 - cell.com
The gut microbiome profoundly affects human health and disease, and their infecting viruses
are likely as important, but often missed because of reference database limitations. Here, we …

Genome-wide detection of single-nucleotide and copy-number variations of a single human cell

C Zong, S Lu, AR Chapman, XS Xie - Science, 2012 - science.org
Kindred cells can have different genomes because of dynamic changes in DNA. Single-cell
sequencing is needed to characterize these genomic differences but has been hindered by …

Gut bacteriophage: current understanding and challenges

TDS Sutton, C Hill - Frontiers in endocrinology, 2019 - frontiersin.org
The gut microbiome is widely accepted to have a significant impact on human health yet,
despite years of research on this complex ecosystem, the contributions of different forces …

Single-cell genome sequencing: current state of the science

C Gawad, W Koh, SR Quake - Nature Reviews Genetics, 2016 - nature.com
The field of single-cell genomics is advancing rapidly and is generating many new insights
into complex biological systems, ranging from the diversity of microbial ecosystems to the …

Single-Cell Genomics Reveals Hundreds of Coexisting Subpopulations in Wild Prochlorococcus

N Kashtan, SE Roggensack, S Rodrigue… - Science, 2014 - science.org
Extensive genomic diversity within coexisting members of a microbial species has been
revealed through selected cultured isolates and metagenomic assemblies. Yet, the cell-by …

MEGAN analysis of metagenomic data

DH Huson, AF Auch, J Qi, SC Schuster - Genome research, 2007 - genome.cshlp.org
Metagenomics is the study of the genomic content of a sample of organisms obtained from a
common habitat using targeted or random sequencing. Goals include understanding the …

[HTML][HTML] Single-neuron sequencing analysis of L1 retrotransposition and somatic mutation in the human brain

GD Evrony, X Cai, E Lee, LB Hills, PC Elhosary… - Cell, 2012 - cell.com
A major unanswered question in neuroscience is whether there exists genomic variability
between individual neurons of the brain, contributing to functional diversity or to an …

Multivariate analyses in microbial ecology

A Ramette - FEMS microbiology ecology, 2007 - academic.oup.com
Environmental microbiology is undergoing a dramatic revolution due to the increasing
accumulation of biological information and contextual environmental parameters. This will …