Vitamin D sources, metabolism, and deficiency: available compounds and guidelines for its treatment

LJ Dominguez, M Farruggia, N Veronese… - Metabolites, 2021 - mdpi.com
Studies on vitamin/hormone D deficiency have received a vast amount of attention in recent
years, particularly concerning recommendations, guidelines, and treatments. Moreover …

Vitamin D: metabolism, molecular mechanism of action, and pleiotropic effects

S Christakos, P Dhawan, A Verstuyf… - Physiological …, 2016 - journals.physiology.org
1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

Physiological bone remodeling: systemic regulation and growth factor involvement

JA Siddiqui, NC Partridge - Physiology, 2016 - journals.physiology.org
Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone
formation and resorption. The balance between the two phases is crucial for sustaining bone …

Diet and fertility: a review

AJ Gaskins, JE Chavarro - American journal of obstetrics and gynecology, 2018 - Elsevier
The literature on the relationship between diet and human fertility has greatly expanded over
the last decade, resulting in the identification of a few clear patterns. Intake of supplemental …

[HTML][HTML] Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy

MH Sherman, TY Ruth, DD Engle, N Ding, AR Atkins… - Cell, 2014 - cell.com
The poor clinical outcome in pancreatic ductal adenocarcinoma (PDA) is attributed to
intrinsic chemoresistance and a growth-permissive tumor microenvironment. Conversion of …

Role of vitamin D in cognitive dysfunction: new molecular concepts and discrepancies between animal and human findings

Z Gáll, O Székely - Nutrients, 2021 - mdpi.com
Purpose of review: increasing evidence suggests that besides the several metabolic,
endocrine, and immune functions of 1alpha, 25-dihydroxyvitamin D (1, 25 (OH) 2D), the …

[HTML][HTML] Maternal mineral and bone metabolism during pregnancy, lactation, and post-weaning recovery

CS Kovacs - Physiological reviews, 2016 - journals.physiology.org
During pregnancy and lactation, female physiology adapts to meet the added nutritional
demands of fetuses and neonates. An average full-term fetus contains∼ 30 g calcium, 20 g …

The role of vitamin D in the endocrinology controlling calcium homeostasis

JC Fleet - Molecular and cellular endocrinology, 2017 - Elsevier
Vitamin D and its' metabolites are a crucial part of the endocrine system that controls whole
body calcium homeostasis. The goal of this hormonal control is to regulate serum calcium …

Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease

DW Eyles, THJ Burne, JJ McGrath - Frontiers in neuroendocrinology, 2013 - Elsevier
Increasingly vitamin D deficiency is being associated with a number of psychiatric
conditions. In particular for disorders with a developmental basis, such as autistic spectrum …

The nonskeletal effects of vitamin D: an Endocrine Society scientific statement

CJ Rosen, JS Adams, DD Bikle, DM Black… - Endocrine …, 2012 - academic.oup.com
Significant controversy has emerged over the last decade concerning the effects of vitamin D
on skeletal and nonskeletal tissues. The demonstration that the vitamin D receptor is …