S Christakos, P Dhawan, A Verstuyf… - Physiological …, 2016 - journals.physiology.org
1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …
Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone formation and resorption. The balance between the two phases is crucial for sustaining bone …
AJ Gaskins, JE Chavarro - American journal of obstetrics and gynecology, 2018 - Elsevier
The literature on the relationship between diet and human fertility has greatly expanded over the last decade, resulting in the identification of a few clear patterns. Intake of supplemental …
The poor clinical outcome in pancreatic ductal adenocarcinoma (PDA) is attributed to intrinsic chemoresistance and a growth-permissive tumor microenvironment. Conversion of …
Purpose of review: increasing evidence suggests that besides the several metabolic, endocrine, and immune functions of 1alpha, 25-dihydroxyvitamin D (1, 25 (OH) 2D), the …
During pregnancy and lactation, female physiology adapts to meet the added nutritional demands of fetuses and neonates. An average full-term fetus contains∼ 30 g calcium, 20 g …
JC Fleet - Molecular and cellular endocrinology, 2017 - Elsevier
Vitamin D and its' metabolites are a crucial part of the endocrine system that controls whole body calcium homeostasis. The goal of this hormonal control is to regulate serum calcium …
Increasingly vitamin D deficiency is being associated with a number of psychiatric conditions. In particular for disorders with a developmental basis, such as autistic spectrum …
Significant controversy has emerged over the last decade concerning the effects of vitamin D on skeletal and nonskeletal tissues. The demonstration that the vitamin D receptor is …