SMC-based immunity against extrachromosomal DNA elements
HW Liu, F Roisné-Hamelin… - Biochemical Society …, 2023 - portlandpress.com
SMC and SMC-like complexes promote chromosome folding and genome maintenance in
all domains of life. Recently, they were also recognized as factors in cellular immunity …
all domains of life. Recently, they were also recognized as factors in cellular immunity …
The SMC5/6 complex: folding chromosomes back into shape when genomes take a break
S Roy, H Adhikary, D D'Amours - Nucleic Acids Research, 2024 - academic.oup.com
High-level folding of chromatin is a key determinant of the shape and functional state of
chromosomes. During cell division, structural maintenance of chromosome (SMC) …
chromosomes. During cell division, structural maintenance of chromosome (SMC) …
Loop-extruding Smc5/6 organizes transcription-induced positive DNA supercoils
The structural maintenance of chromosomes (SMC) protein complexes—cohesin,
condensin, and the Smc5/6 complex (Smc5/6)—are essential for chromosome function. At …
condensin, and the Smc5/6 complex (Smc5/6)—are essential for chromosome function. At …
RAD18 directs DNA double-strand break repair by homologous recombination to post-replicative chromatin
M Palek, N Palkova, P Kleiblova, Z Kleibl… - Nucleic Acids …, 2024 - academic.oup.com
RAD18 is an E3 ubiquitin ligase that prevents replication fork collapse by promoting DNA
translesion synthesis and template switching. Besides this classical role, RAD18 has been …
translesion synthesis and template switching. Besides this classical role, RAD18 has been …
[HTML][HTML] SMC5/6-Mediated Transcriptional Regulation of Hepatitis B Virus and Its Therapeutic Potential
J Bächer, L Allweiss, M Dandri - Viruses, 2024 - mdpi.com
Cells have developed various mechanisms to counteract viral infections. In an evolutionary
arms race, cells mobilize cellular restriction factors to fight off viruses, targeted by viral …
arms race, cells mobilize cellular restriction factors to fight off viruses, targeted by viral …
All eukaryotic SMC proteins induce a twist of-0.6 at each DNA-loop-extrusion step
R Janissen, R Barth, IF Davidson, M Taschner… - bioRxiv, 2024 - biorxiv.org
Eukaryotes carry three types of Structural Maintenance of Chromosomes (SMC) protein
complexes, condensin, cohesin, and SMC5/6, which are ATP-dependent motor proteins that …
complexes, condensin, cohesin, and SMC5/6, which are ATP-dependent motor proteins that …
Structural Maintenance of Chromosomes Complexes
K Jeppsson - Computational Methods for 3D Genome Analysis, 2024 - Springer
Abstract The Structural Maintenance of Chromosomes (SMC) protein complexes are DNA-
binding molecular machines required to shape chromosomes into functional units and to …
binding molecular machines required to shape chromosomes into functional units and to …