The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …

Obesity and type 2 diabetes account for a considerable proportion of the global burden of
age-related metabolic diseases. In age-related metabolic diseases, tissue crosstalk and …

Spexin (SPX) is a 14 aa peptide discovered in 2007 using bioinformatics methods. SPX
inhibits food intake and regulates lipid, and carbohydrate metabolism. Here, we evaluate the …

The aim of this study was to examine the acute effect of aerobic exercise when performed in
the morning and evening on obesity-related hormones of asprosin, spexin, lipocalin-2, and …

Spexin is a novel neuropeptide playing an emerging role in metabolic diseases such as
obesity and diabetes via involvement in energy homeostasis and food intake. The present …

Physical inactivity is a major cause of chronic diseases. It shortens the health span by
lowering the age of the first chronic disease onset, which leads to decreased quality of life …

Objective To compare the effects of resistance and aerobic training (RT and AT) on spexin
(SPX), appetite, lipid accumulation product (LAP), visceral adiposity index (VAI), and body …

Abstract Spexin (SPX) is a 14-amino acid neuropeptide, discovered recently using
bioinformatic techniques. It is encoded by the Ch12: orf39 gene that is widely expressed in …

Spexin is the most recently discovered member of the galanin/kisspeptin/spexin family of
peptides. This 14-amino acid peptide is highly conserved and is implicated in homeostatic …

Recent preclinical and clinical studies have indicated that the galanin peptide family may
regulate glucose metabolism and alleviate insulin resistance, which diminishes the …