Models of cardiac tissue electrophysiology: progress, challenges and open questions

RH Clayton, O Bernus, EM Cherry, H Dierckx… - Progress in biophysics …, 2011 - Elsevier
Models of cardiac tissue electrophysiology are an important component of the Cardiac
Physiome Project, which is an international effort to build biophysically based multi-scale …

Gastrointestinal system

LK Cheng, G O'Grady, P Du, JU Egbuji… - … Systems Biology and …, 2010 - Wiley Online Library
The functions of the gastrointestinal (GI) tract include digestion, absorption, excretion, and
protection. In this review, we focus on the electrical activity of the stomach and small …

Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017

D Dicker, G Nguyen, D Abate, KH Abate, SM Abay… - The lancet, 2018 - thelancet.com
Background Assessments of age-specific mortality and life expectancy have been done by
the UN Population Division, Department of Economics and Social Affairs (UNPOP), the …

[HTML][HTML] A comprehensive and biophysically detailed computational model of the whole human heart electromechanics

M Fedele, R Piersanti, F Regazzoni, M Salvador… - Computer Methods in …, 2023 - Elsevier
While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …

Electromechanics of the heart: a unified approach to the strongly coupled excitation–contraction problem

S Göktepe, E Kuhl - Computational mechanics, 2010 - Springer
This manuscript is concerned with a novel, unified finite element approach to fully coupled
cardiac electromechanics. The intrinsic coupling arises from both the excitation-induced …

Cyber–physical modeling of implantable cardiac medical devices

Z Jiang, M Pajic, R Mangharam - Proceedings of the IEEE, 2011 - ieeexplore.ieee.org
The design of bug-free and safe medical device software is challenging, especially in
complex implantable devices that control and actuate organs in unanticipated contexts …

Mathematical modeling of electrocardiograms: a numerical study

M Boulakia, S Cazeau, MA Fernández… - Annals of biomedical …, 2010 - Springer
This paper deals with the numerical simulation of electrocardiograms (ECG). Our aim is to
devise a mathematical model, based on partial differential equations, which is able to …

Computational modeling of the human atrial anatomy and electrophysiology

O Dössel, MW Krueger, FM Weber, M Wilhelms… - Medical & biological …, 2012 - Springer
This review article gives a comprehensive survey of the progress made in computational
modeling of the human atria during the last 10 years. Modeling the anatomy has emerged …

Ultrafast four-dimensional imaging of cardiac mechanical wave propagation with sparse optoacoustic sensing

Ç Özsoy, A Özbek, M Reiss… - Proceedings of the …, 2021 - National Acad Sciences
Propagation of electromechanical waves in excitable heart muscles follows complex
spatiotemporal patterns holding the key to understanding life-threatening arrhythmias and …

OpenCMISS: a multi-physics & multi-scale computational infrastructure for the VPH/Physiome project

C Bradley, A Bowery, R Britten, V Budelmann… - Progress in biophysics …, 2011 - Elsevier
The VPH/Physiome Project is developing the model encoding standards CellML (cellml. org)
and FieldML (fieldml. org) as well as web-accessible model repositories based on these …