Exosomal noncoding RNAs in gynecological cancers: implications for therapy resistance and biomarkers

C Xu, P Xu, J Zhang, S He, T Hua, A Huang - Frontiers in Oncology, 2024 - frontiersin.org
Gynecologic cancers, including ovarian cancer (OC), cervical cancer (CC), and endometrial
cancer (EC), pose a serious threat to women's health and quality of life due to their high …

The Reign of Follistatin in Tumors and Their Microenvironment: Implications for Drug Resistance

J Sosa, A Oyelakin, S Sinha - Biology, 2024 - mdpi.com
Simple Summary Within the extracellular milieu surrounding cancer cells exists an
ecosystem of heterogeneous cell populations that dictate tumor growth and survival via cell …

Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production

AC Sharrow, E Megill, AJ Chen, A Farooqi… - Molecular …, 2024 - Elsevier
Quiescence is a reversible cell cycle exit traditionally thought to be associated with a
metabolically inactive state. Recent work in muscle cells indicates that metabolic …

Decoding key cell sub-populations and molecular alterations in glioblastoma at recurrence by single-cell analysis

X Wang, Q Sun, W Wang, B Liu, Y Gu… - Acta Neuropathologica …, 2023 - Springer
Glioblastoma (GBM) is the most frequent malignant brain tumor, the relapse of which is
unavoidable following standard treatment. However, the effective treatment for recurrent …

Screening and identification of key biomarkers associated with endometriosis using bioinformatics and next-generation sequencing data analysis

B Vastrad, C Vastrad - Egyptian Journal of Medical Human Genetics, 2024 - Springer
Background Endometriosis is a common cause of endometrial-type mucosa outside the
uterine cavity with symptoms such as painful periods, chronic pelvic pain, pain with …

Identification of the MRTFA/SRF pathway as a critical regulator of quiescence in cancer

S Panesso-Gomez, AJ Cole, A Wield, VI Anyaeche… - …, 2024 - pmc.ncbi.nlm.nih.gov
Chemoresistance is a major driver of cancer deaths. One understudied mechanism of
chemoresistance is quiescence. We used single cell culture to identify, retrieve, and RNA …