The different faces of the macrophage in asthma

TA van der Veen, LES de Groot… - Current opinion in …, 2020 - journals.lww.com
The different faces of the macrophage in asthma : Current Opinion in Pulmonary Medicine The
different faces of the macrophage in asthma : Current Opinion in Pulmonary Medicine Log in or …

Research progress of metabolomics in asthma

C Wang, S Jiang, S Zhang, Z Ouyang, G Wang, F Wang - Metabolites, 2021 - mdpi.com
Asthma is a highly heterogeneous disease, but the pathogenesis of asthma is still unclear. It
is well known that the airway inflammatory immune response is the pathological basis of …

[PDF][PDF] Role of oxidative stress in the pathogenesis of COPD

F Nucera, S Mumby, KR Paudel, V Dharwal… - Minerva …, 2022 - opus.lib.uts.edu.au
Chronic inhalation of cigarette smoke is a prominent cause of chronic obstructive pulmonary
disease (COPD) and provides an important source of exogenous oxidants. In addition …

[HTML][HTML] Uric acid pathway activation during respiratory virus infection promotes Th2 immune response via innate cytokine production and ILC2 accumulation

W Fonseca, CA Malinczak, CF Schuler, SKK Best… - Mucosal …, 2020 - Elsevier
Respiratory syncytial virus (RSV) infects a majority of infants and can cause severe disease
leading to increased risk to develop asthma later in life. In the present studies we detected …

Blocking Notch3 signaling abolishes MUC5AC production in airway epithelial cells from individuals with asthma

AT Reid, KS Nichol, P Chander Veerati… - American journal of …, 2020 - atsjournals.org
In asthma, goblet cell numbers are increased within the airway epithelium, perpetuating the
production of mucus that is more difficult to clear and results in airway mucus plugging …

Screen-printed glucose sensors modified with cellulose nanocrystals (CNCs) for cell culture monitoring

Y Tang, K Petropoulos, F Kurth, H Gao, D Migliorelli… - Biosensors, 2020 - mdpi.com
Glucose sensors are potentially useful tools for monitoring the glucose concentration in cell
culture medium. Here, we present a new, low-cost, and reproducible sensor based on a …

[HTML][HTML] The mechanism and significance of the conversion of xanthine dehydrogenase to xanthine oxidase in mammalian secretory gland cells

T Kusano, T Nishino, K Okamoto, R Hille, T Nishino - Redox Biology, 2023 - Elsevier
The conversion of xanthine dehydrogenase (XDH) to xanthine oxidase (XO) occurs only in
mammalian species. In fresh bovine milk, the enzyme exists predominantly as the oxidase …

The impact of cigarette smoke exposure, COPD, or asthma status on ABC transporter gene expression in human airway epithelial cells

JA Aguiar, A Tamminga, B Lobb, RD Huff, JP Nguyen… - Scientific reports, 2019 - nature.com
ABC transporters are conserved in prokaryotes and eukaryotes, with humans expressing 48
transporters divided into 7 classes (ABCA, ABCB, ABCC, ABCD, ABDE, ABCF, and ABCG) …

Inhibition of uric acid or IL‐1β ameliorates respiratory syncytial virus immunopathology and development of asthma

CF Schuler IV, CA Malinczak, SKK Best, SB Morris… - Allergy, 2020 - Wiley Online Library
Background Respiratory syncytial virus (RSV) affects most infants early in life and is
associated with increased asthma risk. The specific mechanism remains unknown. Objective …

Metabolomic profiling differences among asthma, COPD, and healthy subjects: a LC-MS-based metabolomic analysis

Y Liang, XY Gai, C Chang, X Zhang, W Juan… - Biomedical and …, 2019 - Elsevier
Objective Asthma and chronic obstructive pulmonary disease (COPD) feature different
inflammatory and cellular profiles in the airways, indicating that the cellular metabolic …