Cisplatin-induced gastrointestinal toxicity: An update on possible mechanisms and on available gastroprotective strategies
F Shahid, Z Farooqui, F Khan - European Journal of Pharmacology, 2018 - Elsevier
Abstract Cisplatin (cis-diamminedichloroplatinum [II], CP) is most widely prescribed in
chemotherapy and efficaciously treats diverse human cancers, with remission rates> 90% in …
chemotherapy and efficaciously treats diverse human cancers, with remission rates> 90% in …
Synergistic protective effects of lycopene and N-acetylcysteine against cisplatin-induced hepatorenal toxicity in rats
Cisplatin (CP) is one of the most frequently used chemotherapy agents. The objective of this
design was to determine the ameliorative effect of lycopene (LP) and/or N-acetylcysteine …
design was to determine the ameliorative effect of lycopene (LP) and/or N-acetylcysteine …
Royal jelly modulates oxidative stress and apoptosis in liver and kidneys of rats treated with cisplatin
A Karadeniz, N Simsek, E Karakus… - Oxidative medicine …, 2011 - Wiley Online Library
Cisplatin (CDDP) is one of the most active cytotoxic agents in the treatment of cancer and
has adverse side effects such as nephrotoxicity and hepatotoxicity. The present study was …
has adverse side effects such as nephrotoxicity and hepatotoxicity. The present study was …
The role of L-carnitine in kidney disease and related metabolic dysfunctions
T Ulinski, M Cirulli, MA Virmani - Kidney and Dialysis, 2023 - mdpi.com
Kidney disease is associated with a wide variety of metabolic abnormalities that accompany
the uremic state and the state of dialysis dependence. These include altered L-carnitine …
the uremic state and the state of dialysis dependence. These include altered L-carnitine …
Mechanism of valproic acid‐induced Fanconi syndrome involves mitochondrial dysfunction and oxidative stress in rat kidney
Aim Drug‐induced kidney proximal tubular injury and renal failure (Fanconi syndrome; FS)
is a clinical complication. Valproic acid (VPA) is among the FS‐inducing drugs. The current …
is a clinical complication. Valproic acid (VPA) is among the FS‐inducing drugs. The current …
L-carnitine mitigates oxidative stress and disorganization of cytoskeleton intermediate filaments in cisplatin-induced hepato-renal toxicity in rats
Cisplatin (CP) is one of the most active medications in cancer treatment and has some
adverse effects such as hepatotoxicity and nephrotoxicity. The present research was …
adverse effects such as hepatotoxicity and nephrotoxicity. The present research was …
Myricetin abrogates cisplatin-induced oxidative stress, inflammatory response, and goblet cell disintegration in colon of wistar rats
Cisplatin [cis-diamminedichloroplatinum II] is an extensively prescribed drug in cancer
chemotherapy; it is also useful for the treatment of diverse types of malignancies …
chemotherapy; it is also useful for the treatment of diverse types of malignancies …
Multifunction‐Harnessed Afterglow Nanosensor for Molecular Imaging of Acute Kidney Injury In Vivo
Afterglow is superior to other optical modalities for biomedical applications in that it can
exclude the autofluorescence background. Nevertheless, afterglow has rarely been applied …
exclude the autofluorescence background. Nevertheless, afterglow has rarely been applied …
L-Carnitine alleviates hepatic and renal mitochondrial-dependent apoptotic progression induced by letrozole in female rats through modulation of Nrf-2, Cyt c and …
Letrozole (LTZ) is a non-steroidal aromatase inhibitor that is commonly used in breast
cancer therapy. It has several side effects that might lead to the drug's cessation and data of …
cancer therapy. It has several side effects that might lead to the drug's cessation and data of …
Ameliorative effect of riboflavin on the cisplatin induced nephrotoxicity and hepatotoxicity under photoillumination
Cisplatin is a widely used anticancer drug. It is documented that it elicits major side effects
like nephrotoxicity and hepatotoxicity due to oxidative stress forcing the patients to limit its …
like nephrotoxicity and hepatotoxicity due to oxidative stress forcing the patients to limit its …