Of all biologic matrices, decellularized extracellular matrix (dECM) has emerged as a
promising tool used either alone or when combined with other biologics in the fields of tissue …

Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …

The transition from a fetus to a newborn is the most complex physiologic adaptation that
occurs in human experience. Before medicalization of delivery, the transition had to occur …

Transcriptional regulation contributes to the maintenance of pluripotency, self-renewal and
differentiation in embryonic cells and in stem cells. Therefore, control of gene expression at …

Developmental lung biology is a field that has the potential for significant human impact:
lung disease at the extremes of age continues to cause major morbidity and mortality …

During the development of the pulmonary vasculature in the fetus, many structural and
functional changes occur to prepare the lung for the transition to air breathing. The …

Objectives To examine operative and perinatal aspects of fetal endoscopic tracheal
occlusion (FETO) in congenital diaphragmatic hernia (CDH). Methods This was a …

Experimental studies that are relevant to human pregnancy rely on the selection of
appropriate animal models as an important element in experimental design. Consideration …

The lung is a unique organ in that it is exposed to physical forces derived from breathing,
blood flow, and surface tension throughout life. Over the past decade, significant progress …

Mechanical forces are increasingly recognized to regulate morphogenesis, but how this is
accomplished in the context of the multiple tissue types present within a developing organ …