Flavonoids targeting cancer stem cells for augmenting cancer therapeutics

A Meerson, S Khatib, J Mahajna - International Journal of Molecular …, 2021 - mdpi.com
Cancer stem cells (CSC) have been identified in several types of solid tumors. In some
cases, CSC may be the source of all the tumor cells, the cause of the tumor's resistance to …

Unveiling the power of flavonoids: A dynamic exploration of their impact on cancer through matrix metalloproteinases regulation

P Rajendran - BioMedicine, 2024 - pmc.ncbi.nlm.nih.gov
Cancer stands as a significant contributor to global mortality rates, primarily driven by its
progression and widespread dissemination. Despite notable strides in cancer therapy, the …

Anticancer potential of apigenin and isovitexin with focus on oncogenic metabolism in cancer stem cells

M Ghanbari-Movahed, S Shafiee, JT Burcher, R Lagoa… - Metabolites, 2023 - mdpi.com
It has been demonstrated that cancer stem cells (CSCs) go through metabolic changes that
differentiate them from non-CSCs. The altered metabolism of CSCs plays a vital role in …

Stage-specific effect of inositol hexaphosphate on cancer stem cell pool during growth and progression of prostate tumorigenesis in TRAMP model

K Raina, K Kandhari, AK Jain, K Ravichandran… - Cancers, 2022 - mdpi.com
Simple Summary The stage of a tumor during cancer intervention is the most crucial factor
that determines the treatment regimen. Several bioactive natural compounds have shown …

[HTML][HTML] Comparative Pre-clinical Efficacy of Chinese and Indian Cultivars of Bitter Melon (Momordica charantia) against Pancreatic Cancer

K Kandhari, S Paudel, K Raina, C Agarwal… - Journal of cancer …, 2021 - ncbi.nlm.nih.gov
Given the high rates of incidence and mortality associated with pancreatic cancer (PanC),
there is a need to develop alternative strategies to target PanC. Recent studies have …