The crosstalk between HIFs and mitochondrial dysfunctions in cancer development

X Bao, J Zhang, G Huang, J Yan, C Xu, Z Dou… - Cell Death & …, 2021 - nature.com
Mitochondria are essential cellular organelles that are involved in regulating cellular energy,
metabolism, survival, and proliferation. To some extent, cancer is a genetic and metabolic …

[HTML][HTML] Innovative strategies for photodynamic therapy against hypoxic tumor

X Li, L Chen, M Huang, S Zeng, J Zheng, S Peng… - Asian Journal of …, 2023 - Elsevier
Photodynamic therapy (PDT) is applied as a robust therapeutic option for tumor, which
exhibits some advantages of unique selectivity and irreversible damage to tumor cells …

[HTML][HTML] Reprogramming of glucose metabolism: the hallmark of malignant transformation and target for advanced diagnostics and treatments

Q Tang, S Wu, B Zhao, Z Li, Q Zhou, Y Yu… - Biomedicine & …, 2024 - Elsevier
Reprogramming of cancer metabolism has become increasingly concerned over the last
decade, particularly the reprogramming of glucose metabolism, also known as the" Warburg …

Immune/hypoxic tumor microenvironment regulation-enhanced photodynamic treatment realized by pH-responsive phase transition-targeting nanobubbles

M Zhao, X Yang, H Fu, C Chen, Y Zhang… - … applied materials & …, 2021 - ACS Publications
Due to a special pathological type of triple-negative breast cancer (TNBC) and the lack of
expression of the estrogen receptor (ER), progesterone receptor (PR), and human …

[HTML][HTML] The Role of AMPK/mTOR Signaling Pathway in Anticancer Activity of Metformin: This paper is dedicated to the 70th anniversary of the founding of Physiologia …

N Chomanicova, A Gazova, A Adamickova… - Physiological …, 2021 - ncbi.nlm.nih.gov
Metformin (MTF) is a widely used drug for the treatment of diabetes mellitus type 2 (DM2)
and frequently used as an adjuvant therapy for polycystic ovarian syndrome, metabolic …

Photodynamic therapy induced cell cycle arrest and cancer cell synchronization

K Moloudi, H Abrahamse, BP George - Frontiers in oncology, 2023 - frontiersin.org
Cell cycle arrest (CCA) is seen as a prime candidate for effective cancer therapy. This
mechanism can help researchers to create new treatments to target cancer cells at particular …

The Mitochondrial ATP Synthase/IF1 Axis in Cancer Progression: Targets for Therapeutic Intervention

S Domínguez-Zorita, JM Cuezva - Cancers, 2023 - mdpi.com
Simple Summary Cancer is a global health problem with high personal and economic
burden worldwide. The reprogramming of metabolism experienced by carcinomas offers a …

[HTML][HTML] Enhancing metformin-induced tumor metabolism destruction by glucose oxidase for triple-combination therapy

R Fan, L Cai, H Liu, H Chen, C Chen, G Guo… - Journal of Pharmaceutical …, 2024 - Elsevier
Despite decades of laboratory and clinical trials, breast cancer remains the main cause of
cancer-related disease burden in women. Considering the metabolism destruction effect of …

TGFβ1 secreted by cancer-associated fibroblasts as an inductor of resistance to photodynamic therapy in squamous cell carcinoma cells

M Gallego-Rentero, M Gutiérrez-Pérez… - Cancers, 2021 - mdpi.com
Simple Summary Photodynamic therapy (PDT) is used for the treatment of in situ cutaneous
squamous cell carcinoma (cSCC), the second most common form of skin cancer, as well as …

Photodynamic therapy (PDT) in oncology

Á Juarranz, Y Gilaberte, S González - Cancers, 2020 - mdpi.com
The issue is focused on Photodynamic Therapy (PDT), which is a minimally invasive
therapeutic modality approved for treatment of several types of cancer and non-oncological …