Endocrinopathies in Hemoglobinopathies: What Is the Role of Iron?

P Evangelidis, TM Venou, B Fani, E Vlachaki… - International Journal of …, 2023 - mdpi.com
Hemoglobinopathies, including β-thalassemia and sickle cell disease (SCD), are common
genetic blood disorders. Endocrine disorders are frequent manifestations of organ damage …

SP1 regulates BMSC osteogenic differentiation through the miR-133a-3p/MAPK3 axis: SP1 regulates osteogenic differentiation of BMSCs

L Zhong, Y Sun, C Wang, R Liu, W Ru, W Dai… - Journal of Orthopaedic …, 2024 - Springer
Background The progression of osteoporosis (OP) can dramatically increase the risk of
fractures, which seriously disturb the life of elderly individuals. Specific protein 1 (SP1) is …

Association between COLIA1 gene polymorphism and bone marrow density in children with beta-thalassemia major.

R Abd Elkareem, W El Malah, K Sobhy… - Menoufia Medical …, 2021 - go.gale.com
Objectives To determine the incidence of SP1 polymorphism in the COLIA1 gene and its
correlation to bone mineral density in patients with beta-thalassemia major (TM) …

Molecular characterization and frequency of transforming growth factor beta 1 gene polymorphism and its relation to bone complications in Egyptian patients with β …

SM Elgawhary, MN Mohammed… - The Egyptian Journal …, 2022 - journals.lww.com
Objective The objective of this study was to determine the frequency of transforming growth
factor beta 1 (TGFβ1) C-509T gene polymorphism and its relation to bone complications in …

[HTML][HTML] Osteoporosis in thalassemia major

PH Yiğitoğlu, R Güzel - Turk J Osteoporos., 2012 - jag.journalagent.com
Amaç: D vitamini, immün sistemdeki etkilerinin yanında kemik sağlığında önemli role
sahiptir. Çalışmamızda HIV-enfekte hastalarda D vitamini eksikliğinin sıklığını ve kemik …

[图书][B] Regulation of osteoclasts by collagen type I degradation fragments: the implications for bone destruction and whole body metabolism in osteogenesis …

I Boraschi-Diaz - 2017 - search.proquest.com
Bone destruction by specialized multinuclear cells, osteoclasts, is important for physiological
processes of bone remodeling and tooth eruption. Osteoclasts are also critical contributors …

Association of type 1 collagen (COLIA1) gene polymorphism with osteoporosis in thalassemia major

AH Abdelhamid, RH Eledel… - Menoufia Medical …, 2020 - menoufia-med-j.com
Objectives The objective of this article is to study the association of COLIA1 gene
polymorphism with osteoporosis in thalassemia major. Background Beta-thalassemia is a …

Association between COLIA1 gene polymorphism and bone marrow density in children with beta-thalassemia major

DS Morgan, KI Sobhy, RM Abd Elkareem… - Menoufia Medical …, 2021 - menoufia-med-j.com
Objectives To determine the incidence of SP1 polymorphism in the COLIA1 gene and its
correlation to bone mineral density in patients with beta-thalassemia major (TM) …

Osteoporosis in Thalassemia major/Talasemi majorde osteoporoz.

PH Yigitoglu, R Guzel - Turkish Journal of Osteoporosis, 2012 - go.gale.com
Thalassemia Major is an inherited blood disorder which leads to ineffective erythropoiesis,
bone marrow expansion, and skeletal deformity. In the last two decades the survival of the …

[PDF][PDF] Osteoporosis in Thalassemia Major

TM Osteoporoz - academia.edu
Thalassemia Major is an inherited blood disorder which leads to ineffective erythropoiesis,
bone marrow expansion, and skeletal deformity. In the last two decades the survival of the …