Role of telomere length in human carcinogenesis

A Tsatsakis, T Oikonomopoulou… - International …, 2023 - spandidos-publications.com
Cancer is considered the most important clinical, social and economic issue regarding
cause‑specific disability‑adjusted life years among all human pathologies. Exogenous …

Identification of prognosis-related genes in the cervical cancer immune microenvironment

L Yang, Y Yang, M Meng, W Wang, S He, Y Zhao… - Gene, 2021 - Elsevier
Background Cervical cancer is the fourth most commonly diagnosed cancer in women
worldwide. The metastasis and invasion of this type of cancer are closely related to the …

Relative telomere length change in colorectal carcinoma and its association with tumor characteristics, gene expression and microsatellite instability

MG Kibriya, M Raza, M Kamal, Z Haq, R Paul… - Cancers, 2022 - mdpi.com
Simple Summary Telomeres are specialized repeat DNA sequences at the ends of each
chromosome. The primary function of telomeres is to prevent genomic instability. Telomeres …

[HTML][HTML] Long noncoding RNA: a resident staff of genomic instability regulation in tumorigenesis

F Guo, L Li, W Yang, J Hu, J Cui - Cancer Letters, 2021 - Elsevier
Genomic instability is an important characteristic of cancer, which promotes clonal evolution
and tumorigenesis by increasing the frequency of gene destruction and loss of genome …

The dynamics of telomere length in primary and metastatic colorectal cancer lesions

M Kroupa, O Kubecek, K Tomasova, P Hanak… - Scientific Reports, 2023 - nature.com
Telomeric sequences, the structures comprised of hexanucleotide repeats and associated
proteins, play a pivotal role in chromosome end protection and preservation of genomic …

Genetic liability to human serum metabolites is causally linked to telomere length: insights from genome-wide Mendelian randomization and metabolic pathways …

J Liu, R Pan - Frontiers in Nutrition, 2024 - frontiersin.org
Background Telomere has been recognized as a biomarker of accelerating aging, and
telomere length (TL) shortening is closely related to diverse chronic illnesses. Human serum …

Telomere Length and Human Carcinogenesis: Liable or Random Finding?

TK Nikolouzakis, A Tsatsakis, J Tsiaoussis - Telomeres, 2025 - taylorfrancis.com
Cancer stands for the most important clinical, social, and economic issue regarding cause-
specific disability-adjusted life years (DALYs) among all human pathologies. Exogenous …

Telomere length sensitive regulation of interleukin receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour …

AK Mukherjee, S Dutta, A Singh, S Sharma, SS Roy… - eLife, 2024 - elifesciences.org
Telomeres are crucial for cancer progression. Immune signalling in the tumour
microenvironment has been shown to be very important in cancer prognosis. However, the …

Possible bradykinesia occurrence in lymphocyte division in Parkinson's disease

Yİ Gemici, İ Taşcı, M Dündar, N Özgen… - … of Experimental and …, 2024 - dergipark.org.tr
Lymphocytes have dopamine receptors, and low dopamine levels increase receptor
synthesis. Lymphocytes may move slower in Parkinson's, which is characterized by low …

The Key Role of Telomerase in The Initiation and Treatment of Colon Cancer: New Advances and Prospects

S Hao, P Wu, Z Xue, Z Yang, Y Liu… - Journal of Research in …, 2023 - satursonpublishing.com
Telomeres are important regions for maintaining genome stability, and their dysfunction is
closely related to the occurrence of colon cancer. This article reviews the recent progress in …