[HTML][HTML] Metabolite interactions between host and microbiota during health and disease: Which feeds the other?

Y Zhang, R Chen, DD Zhang, S Qi, Y Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

Organoids as host models for infection biology–a review of methods

C Aguilar, M Alves da Silva, M Saraiva… - … & Molecular Medicine, 2021 - nature.com
Infectious diseases are a major threat worldwide. With the alarming rise of antimicrobial
resistance and emergence of new potential pathogens, a better understanding of the …

Intracellular lifestyle of Chlamydia trachomatis and host–pathogen interactions

K Stelzner, N Vollmuth, T Rudel - Nature Reviews Microbiology, 2023 - nature.com
In recent years, substantial progress has been made in the understanding of the intracellular
lifestyle of Chlamydia trachomatis and how the bacteria establish themselves in the human …

Interactions between microbiota and cervical epithelial, immune, and mucus barrier

M Dong, Y Dong, J Bai, H Li, X Ma, B Li… - Frontiers in cellular …, 2023 - frontiersin.org
The female reproductive tract harbours hundreds of bacterial species and produces
numerous metabolites. The uterine cervix is located between the upper and lower parts of …

Genome organization and genomics in Chlamydia: whole genome sequencing increases understanding of chlamydial virulence, evolution, and phylogeny

LDW Luu, V Kasimov, S Phillips, GSA Myers… - Frontiers in cellular …, 2023 - frontiersin.org
The genus Chlamydia contains important obligate intracellular bacterial pathogens to
humans and animals, including C. trachomatis and C. pneumoniae. Since 1998, when the …

Chlamydia trachomatis as a Current Health Problem: Challenges and Opportunities

R Rodrigues, C Sousa, N Vale - Diagnostics, 2022 - mdpi.com
Chlamydia is one of the most common sexually transmitted bacterial infections (STIs)
worldwide. It is caused by Chlamydia trachomatis (CT), which is an obligate intracellular …

The inclusion membrane protein IncS is critical for initiation of the Chlamydia intracellular developmental cycle

ME Cortina, RC Bishop, BA DeVasure… - PLoS …, 2022 - journals.plos.org
All Chlamydia species are obligate intracellular bacteria that undergo a unique biphasic
developmental cycle strictly in the lumen of a membrane bound compartment, the inclusion …

Contributions of diverse models of the female reproductive tract to the study of Chlamydia trachomatis-host interactions

FC Walker, I Derré - Current Opinion in Microbiology, 2024 - Elsevier
Highlights•Chlamydia infections have damaging consequences on female reproductive
health.•Diverse model systems are required to understand Chlamydia-host …

[HTML][HTML] Bioengineered Co-culture of organoids to recapitulate host-microbe interactions

MB Kim, S Hwangbo, S Jang, YK Jo - Materials Today Bio, 2022 - Elsevier
The recent spike in the instances of complex physiological host-microbe interactions has
raised the demand for developing in vitro models that recapitulate the microbial …

The IRE1α-XBP1 signaling axis promotes glycolytic reprogramming in response to inflammatory stimuli

BC English, HP Savage, SP Mahan, VE Diaz-Ochoa… - MBio, 2023 - Am Soc Microbiol
Immune cells must be able to adjust their metabolic programs to effectively carry out their
effector functions. Here, we show that the endoplasmic reticulum (ER) stress sensor Inositol …