Few environmental factors have a larger influence on animal energetics than temperature, a
fact that makes thermoregulation a very important process for survival. In general …

Fever is a cardinal symptom of infectious or inflammatory insults, but it can also arise from
noninfectious causes. The fever-inducing agent that has been used most frequently in …

▪ Abstract Hypoxia elicits an array of compensatory responses in animals ranging from
protozoa to mammals. Central among these responses is anapyrexia, the regulated …

Heat stress (HS) adversely affects several physiological responses in organisms, but the
underlying molecular mechanisms involved are yet to be fully understood. l-Citrulline (l-Cit) …

The nervous system acts as a biological thermostat by controlling behaviors that regulate the
warming and cooling of animals. We review the structures responsible for thermoregulation …

ETHNOPHARMACOLOGICAL RELEVANCE: Puerarin is the most abundant isoflavonoid in
Radix Puerariae (Gegen), which has been prescribed as a medicinal herb for treating fever …

The causative/regulatory connections between changes in tissue redox state and fever
induction were investigated herein. Wherefore, LPS, the primary element of bacterial cell …

The mechanism that mediates L-citrulline (L-Cit) hypothermia is poorly understood, and the
involvement of nitric oxide signaling has not been fully elucidated. Therefore, this study …

We tested the hypothesis that nitric oxide (NO) acts in the anteroventral preoptic region
(AVPO) modulating fever. To this end, body core temperature (Tc) of rats was monitored by …

L-Citrulline is a non-protein amino acid that promotes arginine recycling and muscle protein
synthesis. This study investigated whether L-citrulline can exert these functions in heat …