The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …

The lack of in vitro models that represent the native tumor microenvironment is a significant
challenge for cancer research. Two-dimensional (2D) monolayer culture has long been the …

Biophysical cues stemming from the extracellular environment are rapidly transduced into
discernible chemical messages (mechanotransduction) that direct cellular activities–placing …

During morphogenesis, molecular mechanisms that orchestrate biomechanical dynamics
across cells remain unclear. Here, we show a role of guidance receptor Plexin-B2 in …

Tenascin C (TnC) is a glycoprotein highly expressed in the extracellular matrix (ECM) during
development and in the adult central nervous system (CNS) in regions of active …

The tenascin family of glycoproteins comprises four members in vertebrates, of which
tenascin-C (Tnc) and tenascin-R (Tnr) are particularly important in the context of lesions in …

There is a challenging need for the development of new alternative nanostructures that can
allow the coupling and/or encapsulation of therapeutic/diagnostic molecules while reducing …

Peptide‐based supramolecular hydrogels are utilized as functional materials in tissue
engineering, axonal regeneration, and controlled drug delivery. The Arg‐Gly‐Asp (RGD) …

Transplantation of stem cells is a promising potential therapy for central nervous system
disease and injury. The capacity for self-renewal, proliferation of progenitor cells, and multi …

Despite the poor regenerative capacity of the adult central nervous system (CNS) in
mammals, two distinct regions, subventricular zone (SVZ) and the subgranular zone (SGZ) …