Machine learning and its applications for protozoal pathogens and protozoal infectious diseases

RS Hu, AEL Hesham, Q Zou - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
In recent years, massive attention has been attracted to the development and application of
machine learning (ML) in the field of infectious diseases, not only serving as a catalyst for …

Computational biology and machine learning approaches to understand mechanistic microbiome-host interactions

P Sudhakar, K Machiels, B Verstockt… - Frontiers in …, 2021 - frontiersin.org
The microbiome, by virtue of its interactions with the host, is implicated in various host
functions including its influence on nutrition and homeostasis. Many chronic diseases such …

Prediction of protein structure classes by incorporating different protein descriptors into general Chou's pseudo amino acid composition

L Nanni, S Brahnam, A Lumini - Journal of theoretical biology, 2014 - Elsevier
Successful protein structure identification enables researchers to estimate the biological
functions of proteins, yet it remains a challenging problem. The most common method for …

DeNovo: virus-host sequence-based protein–protein interaction prediction

FE Eid, M ElHefnawi, LS Heath - Bioinformatics, 2016 - academic.oup.com
Motivation Can we predict protein–protein interactions (PPIs) of a novel virus with its host?
Three major problems arise: the lack of known PPIs for that virus to learn from, the cost of …

A generalized approach to predicting protein-protein interactions between virus and host

X Zhou, B Park, D Choi, K Han - BMC genomics, 2018 - Springer
Background Viral infection involves a large number of protein-protein interactions (PPIs)
between virus and its host. These interactions range from the initial binding of viral coat …

Thermostable chitinase II from Thermomyces lanuginosus SSBP: Cloning, structure prediction and molecular dynamics simulations

FI Khan, A Govender, K Permaul, S Singh… - Journal of theoretical …, 2015 - Elsevier
Thermomyces lanuginosus is a thermophilic fungus that produces large number of
industrially-significant enzymes owing to their inherent stability at high temperatures and …

A new framework for host-pathogen interaction research

H Yu, L Li, A Huffman, J Beverley, J Hur… - Frontiers in …, 2022 - frontiersin.org
COVID-19 often manifests with different outcomes in different patients, highlighting the
complexity of the host-pathogen interactions involved in manifestations of the disease at the …

Integrated inference and evaluation of host–fungi interaction networks

CW Remmele, CH Luther, J Balkenhol… - Frontiers in …, 2015 - frontiersin.org
Fungal microorganisms frequently lead to life-threatening infections. Within this group of
pathogens, the commensal Candida albicans and the filamentous fungus Aspergillus …

Predicting genome-scale Arabidopsis-Pseudomonas syringae interactome using domain and interolog-based approaches

SS Sahu, T Weirick, R Kaundal - BMC bioinformatics, 2014 - Springer
Background Every year pathogenic organisms cause billions of dollars' worth damage to
crops and livestock. In agriculture, study of plant-microbe interactions is demanding a …

Functional Exposed Amino Acids of BauA as Potential Immunogen Against Acinetobacter baumannii

F Sefid, I Rasooli, A Jahangiri, H Bazmara - Acta biotheoretica, 2015 - Springer
Multidrug-resistant Acinetobacter baumannii is recognized to be among the most difficult
antimicrobial-resistant gram negative bacilli to control and treat. One of the major challenges …