Glutamate is the primary excitatory neurotransmitter in the central nervous system (CNS)
which initiates rapid signal transmission in the synapse before its re-uptake into the …

Oxidative stress has been implicated in the etiology and pathobiology of various
neurodegenerative diseases. At baseline, the cells of the nervous system have the capability …

Amyotrophic lateral sclerosis (ALS) is a multifactorial disease, characterized by a
progressive loss of motor neurons that eventually leads to paralysis and death. The current …

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease, which is characterized by
the degeneration of motor neurons in the motor cortex and the spinal cord and subsequently …

Nowadays, epigenetics is of great research value as a new gateway that can solve the
sophisticated mysteries behind neurodegenerative diseases. Epigenetic mechanisms …

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurodegenerative disease
that leads to the massive loss of motor neurons in cerebrum, brain stem and spinal cord. It …

Amyotrophic lateral sclerosis (ALS) is a progressive and devastating multifactorial
neurodegenerative disorder. Although the pathogenesis of ALS is still not completely …

Prion diseases are transmissible spongiform encephalopathies (TSEs) caused by a
conformational conversion of the native cellular prion protein (PrPC) to an abnormal …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with
motor neuron degeneration, progressive paralysis and finally death. Despite the research …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease. ALS
patients suffer from a progressive loss of motor neurons, leading to respiratory failure within …