Inertial microfluidics has gained significant attention since first being proposed in 2007
owing to the advantages of simplicity, high throughput, precise manipulation, and freedom …

The mutational and phenotypic landscape of tumors is dynamic, requiring constant
monitoring of cancer patients to provide the most up-to-date and effective care. Circulating …

Branched-chain amino acids (BCAAs) supply both carbon and nitrogen in pancreatic
cancers, and increased levels of BCAAs have been associated with increased risk of …

The selection of circulating tumor cells (CTCs) directly from blood as a real-time liquid
biopsy has received increasing attention over the past ten years, and further analysis of …

Molecular analysis of circulating tumor cells (CTCs) at single-cell resolution offers great
promise for cancer diagnostics and therapeutics from simple liquid biopsy. Recent …

Multiphysics microfluidics, which combines multiple functional physical processes in a
microfluidics platform, is an emerging research area that has attracted increasing interest for …

Effective and high-throughput cell sorting are critical technologies in single cell analysis in
biology, medicine and clinical applications. Especially for single cell analysis requiring high …

Adoptive cell therapies require the recovery and expansion of highly potent tumour-
infiltrating lymphocytes (TILs). However, TILs in tumours are rare and difficult to isolate …

Traditional 2D cell cultures do not accurately recapitulate tumor heterogeneity, and
insufficient human cell lines are available. Patient-derived xenograft (PDX) models more …

Magnetic cell sorting is an enabling tool for the isolation of specific cellular subpopulations
for downstream applications and requires the cells to be labeled by a sufficient number of …