Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein primarily
known to mediate homotypic cell contacts in epithelia tissues. Because EpCAM expression …

Background Breast cancer is a notable cause of cancer-related death in women worldwide.
Metastasis to distant organs is responsible for~ 90% of this death. Breast cells convert to …

Circulating extracellular vesicles (EVs) have emerged as a valuable source of cancer
biomarkers. However, the high degree of EV heterogeneity and the complexity of clinical …

Epithelial cell adhesion molecule (EpCAM), which is a transmembrane glycoprotein, is
related to tumor progression. We demonstrated that EpCAM plays important roles in …

Epithelial cell adhesion molecule (EpCAM) is a type I transmembrane protein that is
expressed in the majority of normal epithelial tissues and is overexpressed in most epithelial …

EpCAM, known as an epithelial cell adhesion molecule, plays an essential role in cell
adhesion, migration, metastasis and cell signalling. Rather than acting as an apoptosis …

Background and Objectives: Soluble cell adhesion molecules (sCAMs) play a significant
role in the metastatic potential of breast cancer (BC). They might block lymphocytes and …

While strides in cancer treatment continue to advance, the enduring challenges posed by
cancer metastasis and recurrence persist as formidable contributors to the elevated mortality …

Recombinant epithelial cell adhesion molecule extracellular domain (EpEX) has a high
potential as a candidate for passive and active immunotherapy as well as cancer …

Molecular targeted cancer therapy is a rapidly developing field, driving progress toward
greater treatment efficacy. However, targeted monotherapy often fails due to the …