Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …

Antibodies play an essential role in host defence against pathogens by recognizing
microorganisms or infected cells. Although preventing pathogen entry is one potential …

An outbreak of coronavirus disease 2019 (COVID-19),–, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spread globally. Countermeasures are needed …

Viral infections are dangerous diseases for human health worldwide, which lead to
significant morbidity and mortality each year. Because of their importance and the lack of …

For almost 50 years, ebolaviruses and related filoviruses have been repeatedly reemerging
across the vast equatorial belt of the African continent to cause epidemics of highly fatal …

A decade ago, the value of Nicotiana benthamiana as a tool for plant molecular biologists
was beginning to be appreciated. Scientists were using it to study plant-microbe and protein …

Background Available data on the characteristics of patients with Ebola virus disease (EVD)
and clinical management of EVD in settings outside West Africa, as well as the …

While antibody titers and neutralization are considered the gold standard for the selection of
successful vaccines, these parameters are often inadequate predictors of protective …

Antigen-specific B cells bifurcate into antibody-secreting cells (ASCs) and memory B cells
(MBCs) after infection or vaccination. ASCs (plasmablasts) have been extensively studied in …

Four Ebola patients received care at Emory University Hospital, presenting a unique
opportunity to examine the cellular immune responses during acute Ebola virus infection …