RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

Introduction Nanocarrier-based delivery systems offer multiple benefits to overcome
limitations of the traditional drug dosage forms, such as protection of the drug, enhanced …

Nanoparticles show their promise for improving the efficacy of drugs with a narrow
therapeutic window or low bioavailability, such as anticancer drugs and nucleic acid-based …

Tumor vaccines have been showing a relatively weak response rate in cancer patients,
while deficiencies in delivery efficiency to dendritic cells (DCs), as well as DC-intrinsic …

Fluorescent probes capable of precise detection of atherosclerosis (AS) at an early stage
and fast assessment of anti‐AS drugs in animal level are particularly valuable. Herein, a …

Gene therapy has long been regarded a promising treatment for many diseases, whether
acquired (such as AIDS or cancer) or inherited through a genetic disorder. A drug based on …

There are three major requirements for a nanoparticle to deliver its payload to the tumor.
First, the particles need to be stable in the circulation without releasing the drug prematurely …

Nanomedicine is an emerging field that applies concepts in nanotechnology to develop
novel diagnostics and therapies. Physical and chemical properties of particles, including …

Increasing knowledge about molecular mechanisms of endogenous RNA interference
(RNAi) and small interfering RNAs (siRNAs) has been incorporated into innovative nucleic …

With increasing knowledge on the molecular mechanisms of endogenous RNA interference,
small interfering RNAs (siRNAs) have been emerging as innovative nucleic acid medicines …