The trigeminal nerve is the largest of all cranial nerves. It has three branches that provide the
main sensory innervation of the anterior two-thirds of the head and face. Trigeminal …

Dental pulp stem cells, or DPSC, are neural crest-derived cells with an outstanding capacity
to differentiate along multiple cell lineages of interest for cell therapy. In particular, highly …

Background TN is one of the most common causes of facial pain. A higher prevalence of
psychiatric co-morbidities, especially depressive disorder, has been proven in patients with …

Background Classic trigeminal neuralgia is often treated pharmacologically first. However,
microvascular decompression (MVD) or radiosurgical treatment (RS) can render medication …

Trigeminal neuralgia is the most common neuropathic pain involving the craniofacial region.
Due to the complex pathophysiology, it is therapeutically difficult to manage. Noradrenaline …

Peripheral nerve damage does not fully explain the pathogenesis of trigeminal neuralgia
(TN). Central nervous system changes can follow trigeminal nerve dysfunction. We …

Objectives: Despite the etiology of trigeminal neuralgia has been verified by microvascular
decompression as vascular compression of the trigeminal root, very few researches …

Anterior cingulate cortex (ACC) is a critical brain center for chronic pain processing.
Dopamine signaling in the brain has been demonstrated to contribute to descending pain …

Diabetes mellitus (DM) is one of the most common diseases all over the world. The effect of
this endocrine disease on body systems cannot be ignored, where its oral side effects are …

Objective Trigeminal neuralgia is one of the most common causes of facial pain. Our aim is
to investigate the efficacy and borders of percutaneous radiofrequency thermocoagulation in …