Arboviruses such as West Nile, Zika, chikungunya, dengue, and yellow fever viruses have
become highly significant global pathogens through unexpected, explosive outbreaks. While …

Highlights•Host blood components affect mosquito susceptibility to arboviruses in diverse
manners.•The integrity of gut barriers affects the acquisition of viruses from the host's …

Mosquitoes transmit numerous pathogens, but large gaps remain in our understanding of
their physiology. To facilitate explorations of mosquito biology, we have created Aegypti …

Some strains of the inherited bacterium Wolbachia have been shown to be effective at
reducing the transmission of dengue virus (DENV) and other RNA viruses by Aedes aegypti …

Arboviruses such as dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV) viruses infect
close to half a billion people per year, and are primarily transmitted through Aedes aegypti …

Arbovirus infection of Aedes aegypti salivary glands (SGs) determines transmission.
However, there is a dearth of knowledge on SG immunity. Here, we characterized SG …

Variability in how individuals respond to pathogens is a hallmark of infectious disease, yet
the basis for individual variation in host response is often poorly understood. The titer of …

In the mosquito, the midgut epithelium is the initial tissue to become infected with an
arthropod-borne virus (arbovirus) that has been acquired from a vertebrate host along with a …

Mosquitoes are responsible for the transmission of numerous viruses of global health
significance. The term “vector competence” describes the intrinsic ability of an arthropod …

Mosquitoes are widely despised for their exasperating buzzing and irritating bites, and more
poignantly because, during blood-feeding, females may transmit pathogens that cause …