Fisetin and quercetin: promising flavonoids with chemopreventive potential

D Kashyap, VK Garg, HS Tuli, MB Yerer, K Sak… - Biomolecules, 2019 - mdpi.com
Despite advancements in healthcare facilities for diagnosis and treatment, cancer remains
the leading cause of death worldwide. As prevention is always better than cure, efficient …

Fisetin in cancer: attributes, developmental aspects, and nanotherapeutics

RM Kumar, H Kumar, T Bhatt, R Jain, K Panchal… - Pharmaceuticals, 2023 - mdpi.com
Cancer is one of the major causes of mortality, globally. Cancerous cells invade normal cells
and metastasize to distant sites with the help of the lymphatic system. There are several …

Fisetin: A bioactive phytochemical with potential for cancer prevention and pharmacotherapy

D Kashyap, A Sharma, K Sak, HS Tuli, HS Buttar… - Life sciences, 2018 - Elsevier
A wide variety of chronic diseases, such as neurodegenerative and cardiovascular
disorders, diabetes mellitus, osteoarthtitis, obesity and various cancers, are now being …

The potential role of fisetin, a flavonoid in cancer prevention and treatment

AH Rahmani, A Almatroudi, KS Allemailem, AA Khan… - Molecules, 2022 - mdpi.com
Cancer is a main culprit and the second-leading cause of death worldwide. The current
mode of treatment strategies including surgery with chemotherapy and radiation therapy …

A review of molecular mechanisms involved in anticancer and antiangiogenic effects of natural polyphenolic compounds

H Abbaszadeh, B Keikhaei… - Phytotherapy Research, 2019 - Wiley Online Library
The aim of this review is to obtain a further understanding of the reported inhibitory effects of
polyphenols on cancer cell proliferation and angiogenesis process and the probable …

Preparation and optimization of poly (lactic acid) nanoparticles loaded with fisetin to improve anti-cancer therapy

C Feng, X Yuan, K Chu, H Zhang, W Ji, M Rui - International journal of …, 2019 - Elsevier
Fisetin is a natural flavonoid with promising antitumor activity, whereas its clinical application
is limited by its hydrophobic property. In this study, we aimed to load fisetin into poly (lactic …

[HTML][HTML] Flavonoid-liposomes formulations: Physico-chemical characteristics, biological activities and therapeutic applications

EG Halevas, DI Avgoulas, G Katsipis… - European Journal of …, 2022 - Elsevier
Flavonoids constitute a class of naturally derived heterocyclic compounds ubiquitously
distributed in fruits, herbs and vegetables. Until today, flavonoids, as nutritional …

Liposomal encapsulation of the natural flavonoid fisetin improves bioavailability and antitumor efficacy

J Seguin, L Brullé, R Boyer, YM Lu, MR Romano… - International journal of …, 2013 - Elsevier
The natural flavonoid fisetin (3, 3′, 4′, 7-tetrahydroxyflavone) has shown antiangiogenic
and anticancer properties. Because of fisetin limited water solubility, we designed a …

Impact of isoflurane on malignant capability of ovarian cancer in vitro

X Luo, H Zhao, L Hennah, J Ning, J Liu… - British journal of …, 2015 - academic.oup.com
Background Metastatic recurrence of ovarian cancer is the foremost cause of postoperative
mortality. With recent research indicating that inhalation of anaesthetics may influence …

Fisetin inhibited growth and metastasis of triple-negative breast cancer by reversing epithelial-to-mesenchymal transition via PTEN/Akt/GSK3β signal pathway

J Li, X Gong, R Jiang, D Lin, T Zhou, A Zhang… - Frontiers in …, 2018 - frontiersin.org
Triple negative breast cancer (TNBC), characterized by its highly aggressive and metastatic
features, is associated with poor prognosis and high mortality partly due to lack of effective …