Epigenetic mechanisms, which include DNA methylation, histone modification, and
microRNA (miRNA), can produce heritable phenotypic changes without a change in DNA …

The discovery of microRNAs and their role in diseases was a breakthrough that inspired
research into microRNAs as drug targets. Cardiovascular diseases are an area in which …

Micro RNA s (mi RNA s) have within the past decade emerged as key regulators of
metabolic homoeostasis. Major tissues in intermediary metabolism important during …

With the increasing incidence of thoracic tumors, radiation therapy (RT) has become an
important component of comprehensive treatment. RT improves survival in many cancers …

Disease is often the result of an aberrant or inadequate response to physiologic and
pathophysiologic stress. Studies over the last 10 years have uncovered a recurring …

Cardiovascular diseases are one of the most common causes of death in both developing
and developed countries worldwide. Even though there have been improvements in primary …

In recent years, prominent roles for microRNAs (miRNAs) have been uncovered in several
cardiovascular disorders. The ability to therapeutically manipulate miRNA expression and …

Unintended cardiac fibroblast proliferation in many pathophysiological heart conditions,
known as cardiac fibrosis, results in pooling of extracellular matrix (ECM) proteins in the …

Since their discovery 20 years ago, microRNAs have been related to posttranscriptional
regulation of gene expression in major cardiac physiological and pathological processes …

Pathological growth of cardiomyocytes (hypertrophy) is a major determinant for the
development of heart failure, one of the leading medical causes of mortality worldwide. Here …