Dermatomyositis: clinical features and pathogenesis

ME DeWane, R Waldman, J Lu - Journal of the American Academy of …, 2020 - Elsevier
Dermatomyositis (DM) is an idiopathic inflammatory myopathy that is clinically
heterogeneous and that can be difficult to diagnose. Cutaneous manifestations sometimes …

Current classification and management of inflammatory myopathies

J Schmidt - Journal of neuromuscular diseases, 2018 - content.iospress.com
Inflammatory disorders of the skeletal muscle include polymyositis (PM), dermatomyositis
(DM),(immune mediated) necrotizing myopathy (NM), overlap syndrome with myositis …

Risk factors and disease mechanisms in myositis

FW Miller, JA Lamb, J Schmidt… - Nature Reviews …, 2018 - nature.com
Autoimmune diseases develop as a result of chronic inflammation owing to interactions
between genes and the environment. However, the mechanisms by which autoimmune …

Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups

S Rothwell, H Chinoy, JA Lamb, FW Miller… - Annals of the …, 2019 - ard.bmj.com
Objectives Idiopathic inflammatory myopathies (IIM) are a spectrum of rare autoimmune
diseases characterised clinically by muscle weakness and heterogeneous systemic organ …

Distinctive cutaneous and systemic features associated with antitranscriptional intermediary factor-1γ antibodies in adults with dermatomyositis

DF Fiorentino, K Kuo, L Chung, L Zaba, S Li… - Journal of the American …, 2015 - Elsevier
Background Antibodies against transcriptional intermediary factor (TIF)-1γ are associated
with malignancy in dermatomyositis (DM). Identification of clinical findings associated with …

The juvenile idiopathic inflammatory myopathies: pathogenesis, clinical and autoantibody phenotypes, and outcomes

LG Rider, K Nistala - Journal of internal medicine, 2016 - Wiley Online Library
The aim of this review was to summarize recent advances in the understanding of the
clinical and autoantibody phenotypes, their associated outcomes and the pathogenesis of …

Cutaneous manifestations of dermatomyositis: a comprehensive review

C Mainetti, B Terziroli Beretta-Piccoli… - Clinical reviews in allergy & …, 2017 - Springer
Dermatomyositis (DM) is an idiopathic inflammatory myopathy characterized by the
presence of skin lesions and inflammation of skeletal muscles; however, this feature may be …

Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care

C Papadopoulou, C Chew, MGL Wilkinson… - Nature Reviews …, 2023 - nature.com
The childhood-onset or juvenile idiopathic inflammatory myopathies (JIIMs) are a
heterogenous group of rare and serious autoimmune diseases of children and young …

[HTML][HTML] Polymyositis and dermatomyositis–challenges in diagnosis and management

SH Yang, C Chang, ZX Lian - Journal of translational autoimmunity, 2019 - Elsevier
Polymyositis (PM) and dermatomyositis (DM) are different disease subtypes of idiopathic
inflammatory myopathies (IIMs). The main clinical features of PM and DM include …

[HTML][HTML] Dermatomyositis autoantibodies: how can we maximize utility?

LM Hodgkinson, TT Wu… - Annals of translational …, 2021 - ncbi.nlm.nih.gov
The past 15 years has seen significant advances in the characterization of myositis-specific
autoantibodies (MSAs) and their associated phenotypes in patients with dermatomyositis …