Life of RISC: Formation, action, and degradation of RNA-induced silencing complex

H Iwakawa, Y Tomari - Molecular cell, 2022 - cell.com
Small RNAs regulate a wide variety of biological processes by repressing the expression of
target genes at the transcriptional and post-transcriptional levels. To achieve these …

Plant noncoding RNAs: hidden players in development and stress responses

Y Yu, Y Zhang, X Chen, Y Chen - Annual review of cell and …, 2019 - annualreviews.org
A large and significant portion of eukaryotic transcriptomes consists of noncoding RNAs
(ncRNAs) that have minimal or no protein-coding capacity but are functional. Diverse …

The functions of microRNAs: mRNA decay and translational repression

H Iwakawa, Y Tomari - Trends in cell biology, 2015 - cell.com
MicroRNAs (miRNAs) are a class of endogenous small noncoding RNAs, which regulate
complementary mRNAs by inducing translational repression and mRNA decay. Although …

Plant microRNAs: biogenesis, homeostasis, and degradation

J Wang, J Mei, G Ren - Frontiers in plant science, 2019 - frontiersin.org
MicroRNAs (miRNAs), a class of endogenous, tiny, non-coding RNAs, are master regulators
of gene expression among most eukaryotes. Intracellular miRNA abundance is regulated …

Diversifying microRNA sequence and function

SL Ameres, PD Zamore - Nature reviews Molecular cell biology, 2013 - nature.com
MicroRNAs (miRNAs) regulate the expression of most genes in animals, but we are only
now beginning to understand how they are generated, assembled into functional complexes …

MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship

AE Pasquinelli - Nature Reviews Genetics, 2012 - nature.com
MicroRNAs (miRNAs) have emerged as key gene regulators in diverse biological pathways.
These small non-coding RNAs bind to target sequences in mRNAs, typically resulting in …

Arabidopsis miR156 Regulates Tolerance to Recurring Environmental Stress through SPL Transcription Factors

A Stief, S Altmann, K Hoffmann, BD Pant… - The Plant …, 2014 - academic.oup.com
Plants are sessile organisms that gauge stressful conditions to ensure survival and
reproductive success. While plants in nature often encounter chronic or recurring stressful …

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

E Huntzinger, E Izaurralde - Nature Reviews Genetics, 2011 - nature.com
Despite their widespread roles as regulators of gene expression, important questions
remain about target regulation by microRNAs. Animal microRNAs were originally thought to …

Classification and comparison of small RNAs from plants

MJ Axtell - Annual review of plant biology, 2013 - annualreviews.org
Regulatory small RNAs, which range in size from 20 to 24 nucleotides, are ubiquitous
components of endogenous plant transcriptomes, as well as common responses to …

Regulation of Flowering by Trehalose-6-Phosphate Signaling in Arabidopsis thaliana

V Wahl, J Ponnu, A Schlereth, S Arrivault… - Science, 2013 - science.org
The timing of the induction of flowering determines to a large extent the reproductive
success of plants. Plants integrate diverse environmental and endogenous signals to ensure …